Autophagy mediates degradation of nuclear lamina
Macroautophagy (hereafter referred to as autophagy) is a catabolic membrane trafficking
process that degrades a variety of cellular constituents and is associated with human …
process that degrades a variety of cellular constituents and is associated with human …
Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus
K Mochida, Y Oikawa, Y Kimura, H Kirisako, H Hirano… - Nature, 2015 - nature.com
Macroautophagy (hereafter referred to as autophagy) degrades various intracellular
constituents to regulate a wide range of cellular functions, and is also closely linked to …
constituents to regulate a wide range of cellular functions, and is also closely linked to …
Identifying an essential role of nuclear LC3 for autophagy
R Huang, W Liu - Autophagy, 2015 - Taylor & Francis
MAP1LC3/LC3 (microtubule-associated protein 1 light chain 3), a mammalian ortholog of
yeast Atg8, is a key protein contributing to major steps of autophagy. It has been recognized …
yeast Atg8, is a key protein contributing to major steps of autophagy. It has been recognized …
Autophagosomes form at ER–mitochondria contact sites
M Hamasaki, N Furuta, A Matsuda, A Nezu… - Nature, 2013 - nature.com
Autophagy is a tightly regulated intracellular bulk degradation/recycling system that has
fundamental roles in cellular homeostasis. Autophagy is initiated by isolation membranes …
fundamental roles in cellular homeostasis. Autophagy is initiated by isolation membranes …
Autophagic degradation of nuclear components in mammalian cells
Autophagy is an evolutionally conserved intracellular mechanism for the degradation of
organelles and proteins. Here we demonstrate the presence of perinuclear …
organelles and proteins. Here we demonstrate the presence of perinuclear …
AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy
Autophagy is a highly conserved self-digestion process, which is essential for maintaining
homeostasis and viability in response to nutrient starvation,,,. Although the components of …
homeostasis and viability in response to nutrient starvation,,,. Although the components of …
Autophagy fights disease through cellular self-digestion
Autophagy, or cellular self-digestion, is a cellular pathway involved in protein and organelle
degradation, with an astonishing number of connections to human disease and physiology …
degradation, with an astonishing number of connections to human disease and physiology …
Regulation of endoplasmic reticulum turnover by selective autophagy
A Khaminets, T Heinrich, M Mari, P Grumati… - Nature, 2015 - nature.com
The endoplasmic reticulum (ER) is the largest intracellular endomembrane system, enabling
protein and lipid synthesis, ion homeostasis, quality control of newly synthesized proteins …
protein and lipid synthesis, ion homeostasis, quality control of newly synthesized proteins …
[HTML][HTML] Deacetylation of nuclear LC3 drives autophagy initiation under starvation
R Huang, Y Xu, W Wan, X Shou, J Qian, Z You, B Liu… - Molecular cell, 2015 - cell.com
Shuttling of macromolecules between different cellular compartments helps regulate the
timing and extent of different cellular activities. Here, we report that LC3, a key initiator of …
timing and extent of different cellular activities. Here, we report that LC3, a key initiator of …
SIRT1–a new mammalian substrate of nuclear autophagy
Macroautophagic/autophagic degradation of nuclear components (or nuclear autophagy) is
a poorly understood area in autophagy research. We previously reported the nuclear lamina …
a poorly understood area in autophagy research. We previously reported the nuclear lamina …