Background Hematopoietic stem cell transplantation (HSCT) is the only curative treatment
available to severe thalassemic patients. The treatment, however, is very costly, particularly …

Background Hematopoieticic stem cell transplantation is the only therapeutic option that can
cure thalassemia disease. Reduced intensity hematopoietic stem cell transplantation (RI …

Hematopoietic stem cell transplantation (HSCT) is the only cure for thalassemia major (TM),
which inflicts a significant 1-time cost. Hence, it is important to explore the cost effectiveness …

Hematopoietic cell transplantation (HCT) remains the sole available curative option for
patients with β-thalassemia major. Expanded and improved supportive therapies for …

Background Transfusion-dependent thalassaemia (TDT) is a hereditary blood disorder in
which blood transfusion is the mainstay treatment to prolong survival and improve quality of …

Background Patients with transfusion-dependent thalassemia (TDT) require lifelong blood
transfusions and iron chelation therapy. Thus, patients afflicted with TDT often have to …

Thalassemias are the most common inherited genetic disorder in India and a major public
health burden with bone marrow transplant (BMT) considered the only established curative …

The thalassemias are a heterogeneous group of inherited hypochromic anemias of varying
severity. The mainstay of supportive treatment is regular blood transfusion accompanied by …

Objectives Transfusion-dependent β-thalassemia (TDT) is a genetic disease that affects
production of red blood cells. Conventional treatment involves regular red blood cell …

Seventy-five percent of patients with beta thalassemia (β-thalassemia) do not have human
leukocyte antigen–matched siblings and until recently had no access to a curative treatment …