The effect of antibody fragments on CD25 targeted regulatory T cell near-infrared photoimmunotherapy
R Okada, Y Maruoka, A Furusawa, F Inagaki… - Bioconjugate …, 2019 - ACS Publications
Regulatory T (Treg) cells play a major role in immune suppression permitting tumors to
evade immune surveillance. Depletion of intratumoral Treg cells can result in tumor …
evade immune surveillance. Depletion of intratumoral Treg cells can result in tumor …
Comparison of the Effectiveness of IgG Antibody versus F(ab′)2 Antibody Fragment in CTLA4-Targeted Near-Infrared Photoimmunotherapy
T Kato, R Okada, A Furusawa, H Wakiyama… - Molecular …, 2022 - ACS Publications
Near-infrared photoimmunotherapy (NIR-PIT) is a novel cancer treatment modality that
utilizes antibody-photoabsorber conjugates (APCs) and selectively kills target cells after …
utilizes antibody-photoabsorber conjugates (APCs) and selectively kills target cells after …
Combined CD44-and CD25-targeted near-infrared photoimmunotherapy selectively kills cancer and regulatory T cells in syngeneic mouse cancer models
Y Maruoka, A Furusawa, R Okada, F Inagaki… - Cancer immunology …, 2020 - AACR
Near-infrared photoimmunotherapy (NIR-PIT) is a newly developed and selective cancer
treatment that induces necrotic and immunogenic cell death and utilizes a mAb conjugated …
treatment that induces necrotic and immunogenic cell death and utilizes a mAb conjugated …
[HTML][HTML] Near infrared photoimmunotherapy; a review of targets for cancer therapy
T Kato, H Wakiyama, A Furusawa, PL Choyke… - Cancers, 2021 - mdpi.com
Simple Summary Near-infrared photoimmunotherapy (NIR-PIT) is a newly developed cancer
treatment that uses an antibody-photoabsorber (IRDye700DX) conjugate (APC) that is …
treatment that uses an antibody-photoabsorber (IRDye700DX) conjugate (APC) that is …
CD29 targeted near-infrared photoimmunotherapy (NIR-PIT) in the treatment of a pigmented melanoma model
A Furusawa, R Okada, F Inagaki, H Wakiyama… - …, 2022 - Taylor & Francis
Near-infrared photoimmunotherapy (NIR-PIT) is a newly developed cancer treatment that
utilizes an antibody-photoabsorber-conjugate (AbPC) combined with NIR light. The AbPC is …
utilizes an antibody-photoabsorber-conjugate (AbPC) combined with NIR light. The AbPC is …
Near-infrared photoimmunotherapy and anti-cancer immunity
K Nakajima, M Ogawa - International Immunology, 2024 - academic.oup.com
The activation of the anti-cancer immune system is an important strategy to control cancer. A
new form of cancer phototherapy, near-infrared photoimmunotherapy (NIR-PIT), was …
new form of cancer phototherapy, near-infrared photoimmunotherapy (NIR-PIT), was …
Near-infrared photoimmunotherapy induced tumor cell death enhances tumor dendritic cell migration
T Moriya, M Hashimoto, H Matsushita… - Cancer Immunology …, 2022 - Springer
Near-infrared photoimmunotherapy (NIR-PIT) selectively kills tumor cells to which the photo-
absorber dye IR700DX-conjugated antibodies are bound and induces a systemic anti-tumor …
absorber dye IR700DX-conjugated antibodies are bound and induces a systemic anti-tumor …
[HTML][HTML] Increased immunogenicity of a minimally immunogenic tumor after cancer-targeting near infrared photoimmunotherapy
H Wakiyama, A Furusawa, R Okada, F Inagaki, T Kato… - Cancers, 2020 - mdpi.com
Simple Summary Near-infrared photoimmunotherapy (NIR-PIT) is a highly selective cancer
treatment that employs an antibody photoabsorber conjugate (APC) composed of a targeting …
treatment that employs an antibody photoabsorber conjugate (APC) composed of a targeting …
Spatially selective depletion of tumor-associated regulatory T cells with near-infrared photoimmunotherapy
K Sato, N Sato, B Xu, Y Nakamura, T Nagaya… - Science translational …, 2016 - science.org
Current immunotherapies for cancer seek to modulate the balance among different immune
cell populations, thereby promoting antitumor immune responses. However, because these …
cell populations, thereby promoting antitumor immune responses. However, because these …
[HTML][HTML] Near infrared photoimmunotherapy for cancers: A translational perspective
Y Maruoka, H Wakiyama, PL Choyke, H Kobayashi - EBioMedicine, 2021 - thelancet.com
Near-infrared photoimmunotherapy (NIR-PIT) is a newly-developed, highly-selective cancer
treatment, which utilizes a monoclonal antibody conjugated to a photoabsorbing dye …
treatment, which utilizes a monoclonal antibody conjugated to a photoabsorbing dye …