Cognitive decline in adults with amnestic mild cognitive impairment and high amyloid-β: prodromal Alzheimer's disease?
We aimed to characterize the nature and magnitude of cognitive decline in a group of adults
with amnestic mild cognitive impairment (aMCI) with high and low levels of amyloid-(A) in …
with amnestic mild cognitive impairment (aMCI) with high and low levels of amyloid-(A) in …
Cognitive consequences of high Aβ amyloid in mild cognitive impairment and healthy older adults: Implications for early detection of Alzheimer's disease.
Background: It has been proposed that only mild cognitive impairment (MCI) with high Aβ
amyloid is indicative of incipient Alzheimer's disease (AD), yet MCI with low Aβ amyloid may …
amyloid is indicative of incipient Alzheimer's disease (AD), yet MCI with low Aβ amyloid may …
Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer's disease
High amyloid has been associated with substantial episodic memory decline over 18 and 36
months in healthy older adults and individuals with mild cognitive impairment. However, the …
months in healthy older adults and individuals with mild cognitive impairment. However, the …
Decline in cognitive function over 18 months in healthy older adults with high amyloid-β
We aimed to characterize the nature and magnitude of cognitive decline in a group of
healthy older adults with high and low levels of amyloid-(A) and who were APOE 4 carriers …
healthy older adults with high and low levels of amyloid-(A) and who were APOE 4 carriers …
Amyloid-β related memory decline is not associated with subjective or informant rated cognitive impairment in healthy adults
Background: The detection of early Alzheimer's disease (AD) can rely on subjective and
informant reports of cognitive impairment. However, relationships between subjective …
informant reports of cognitive impairment. However, relationships between subjective …
Mild cognitive impairment due to Alzheimer disease is less likely under the age of 65
S Shin, JH Kim, JH Cho, GS Kim, SA Choi… - Alzheimer Disease & …, 2015 - journals.lww.com
Patients with amnestic mild cognitive impairment (aMCI) are considered to have a high risk
for Alzheimer dementia (AD). Even high positive predictive values, however, cannot be …
for Alzheimer dementia (AD). Even high positive predictive values, however, cannot be …
[HTML][HTML] Neuropsychology and neuroimaging profiles of amyloid-positive versus amyloid-negative amnestic mild cognitive impairment patients
C Tomadesso, V de La Sayette, R de Flores… - Alzheimer's & Dementia …, 2018 - Elsevier
Introduction Patients with amnestic mild cognitive impairment (aMCI) are heterogeneous as
regard to their amyloid status. The present study aimed at highlighting the …
regard to their amyloid status. The present study aimed at highlighting the …
The association of Aβ amyloid and composite cognitive measures in healthy older adults and MCI
Background: To date evidence of the relationship between cognition and Aβ amyloid during
the early stages of Alzheimer's Disease (AD) has been inconsistent. This study aimed to …
the early stages of Alzheimer's Disease (AD) has been inconsistent. This study aimed to …
A biomarker study in long-lasting amnestic mild cognitive impairment
Background Mild cognitive impairment (MCI) is a heterogeneous syndrome resulting from
Alzheimer's disease (AD) as well as to non-AD and non-neurodegenerative conditions. A …
Alzheimer's disease (AD) as well as to non-AD and non-neurodegenerative conditions. A …
Amyloid pathology in the progression to mild cognitive impairment
PS Insel, O Hansson, RS Mackin, M Weiner… - Neurobiology of …, 2018 - Elsevier
The objective of this study was to determine the cognitive and functional decline and
development of brain injury in individuals progressing from preclinical (β-amyloid positive …
development of brain injury in individuals progressing from preclinical (β-amyloid positive …
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