The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …

Peptides that recognize specific cell types promise to be valuable tools both in research and
clinical applications. Cell-specific peptides can be useful as drug delivery vehicles …

Although monoclonal antibodies have demonstrated clinical potentials as tumor targeting
agents, poor tumor penetration of the antibodies due to the size of molecules and liver/bone …

Peptides are widely used in pharmaceutical industry as active pharmaceutical ingredients,
versatile tools in drug discovery, and for drug delivery. They find themselves at the …

The field of combinatorial peptide chemistry has emerged as a powerful tool in the study of
many biological systems. This review focuses on combinatorial peptide library methodology …

Over the past year, great strides have been made in the design of peptide libraries, and new
approaches have been developed for identifying peptide ligands. The libraries comprise …

Cancer is one of the major and leading causes of death worldwide. Two of the greatest
challenges in fighting cancer are early detection and effective treatments with no or …

Highlights•Display techniques allow the genetic encoding and screening of billions of
peptides.•Strategies were developed to chemically modify genetically encoded peptide …

A collection of 60 cell lines derived from human tumors (NCI-60) has been widely explored
as a tool for anticancer drug discovery. Here, we profiled the cell surface of the NCI-60 by …

Several monoclonal antibodies that target cell surface receptors have gained approval by
the US Food and Drug Administration and are widely used in the treatment of some cancers …