Background: Nails contain genomic DNA that can be used for genetic analyses, which is
attractive for large epidemiologic studies that have collected or are planning to collect nail …

Blood samples have traditionally been used as the main source of DNA for genetic analysis.
However, this source can be difficult in terms of collection, transportation, and long-term …

Objectives Nail has been a substitute DNA source for genotyping. To investigate the integrity
and consistency of nail DNA amplification for biomarker study, nail clippings from 12 …

The availability of high-quality germline DNA is an important prerequisite for a variety of
genetic analyses. We have shown previously that fingernail clippings provide an optimal …

Materials and Methods THE NETHERLANDS COHORT STUDY ON DIET AND CANCER
(NLCS) The NLCS is a prospective cohort study, which started in 1986 and includes …

To investigate the feasibility of DNA analysis of nails taken from human remains after
environmental exposure, we tested the quantity and quality of DNA that could be recovered …

Association studies designed to identify the genetic determinants underlying complex
disease increasingly require sustainable high-quality DNA resources for large-scale single …

We report on the successful routine amplification of DNA profiles from small sections of
fingernails using direct PCR. The data are from 40 nail clippings from eight donors where …

Forensic practitioners and crime laboratories regularly collect and analyze fingernail
evidence; however, the best techniques for processing such evidence have not been …

Background Collection of buccal cells from saliva for DNA extraction offers a less invasive
and convenient alternative to venipuncture blood collection that may increase participation …