Hexavalent chromium induces cartilage degeneration and osteoarthritis pathogenesis
GGD Suminda, Y Min, M Kim, Y Heo, K Do, YO Son - Exposure and Health, 2023 - Springer
Abstract Hexavalent chromium (Cr (VI)), an environmental hazard, can damage human
organs and is associated with various diseases when ingested; however, its effects on the …
organs and is associated with various diseases when ingested; however, its effects on the …
[HTML][HTML] Zinc protects articular chondrocytes through changes in Nrf2-mediated antioxidants, cytokines and matrix metalloproteinases
TC Huang, WT Chang, YC Hu, BS Hsieh, HL Cheng… - Nutrients, 2018 - mdpi.com
Osteoarthritis (OA) is an age-related degenerative joint disease characterized by high
oxidative stress, chondrocyte death and cartilage damage. Zinc has been implicated in the …
oxidative stress, chondrocyte death and cartilage damage. Zinc has been implicated in the …
Kaempferol attenuates the effects of XIST/miR-130a/STAT3 on inflammation and extracellular matrix degradation in osteoarthritis
Y Xiao, L Liu, Y Zheng, W Liu, Y Xu - Future medicinal chemistry, 2021 - Taylor & Francis
Aim: To investigate whether kaempferol exhibited protective effects on osteoarthritis
chondrocytes by modulating the XIST/miR-130a/STAT3 axis. Methods: qRT-PCR and …
chondrocytes by modulating the XIST/miR-130a/STAT3 axis. Methods: qRT-PCR and …
MiR‐1207‐5p/CX3CR1 axis Regulates the Progression of Osteoarthritis via the Modulation of the Activity of NF‐κB Pathway
XC Liu, L Xu, YL Cai, ZY Zheng… - International Journal of …, 2020 - Wiley Online Library
Background Osteoarthritis (OA) is a prevalent chronic diseases characterized by formation of
osteophytes and degradation of articular cartilage. Previous evidence has identified the …
osteophytes and degradation of articular cartilage. Previous evidence has identified the …
miR‐1 Inhibits the Ferroptosis of Chondrocyte by Targeting CX43 and Alleviates Osteoarthritis Progression
M Zhou, C Zhai, K Shen, G Liu, L Liu… - Journal of …, 2023 - Wiley Online Library
Dysregulation of miRNAs in chondrocytes has been confirmed to participate in osteoarthritis
(OA) progression. Previous study has screen out several key miRNAs may play crucial role …
(OA) progression. Previous study has screen out several key miRNAs may play crucial role …
Cinnamaldehyde Induces the Expression of MicroRNA-1285-5p and MicroRNA-140-5p in Chondrocytes to Ameliorate the Apoptosis and Inflammatory Response
G Li, Y Song - Cartilage, 2023 - journals.sagepub.com
Objective Cinnamaldehyde (CA) is an active ingredient of Wenyang Tongluo capsule. This
study was performed to investigate the function of CA on human chondrocytes. Design …
study was performed to investigate the function of CA on human chondrocytes. Design …
Comparative chronic in vitro toxicity of hexavalent chromium to osteoblasts and monocytes
VK Raghunathan, JNA Tettey, EM Ellis… - Journal of Biomedical …, 2009 - Wiley Online Library
There is increasing concern regarding the long‐term biological effects of exposure to low
concentrations of metal ions, particularly chromium, in patients following implantation of …
concentrations of metal ions, particularly chromium, in patients following implantation of …
Limonin Inhibits IL‐1β‐Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2
J Jin, X Lv, B Wang, C Ren, J Jiang… - Oxidative Medicine …, 2021 - Wiley Online Library
Osteoarthritis (OA), a degenerative disorder, is considered to be one of the most common
forms of arthritis. Limonin (Lim) is extracted from lemons and other citrus fruits. Limonin has …
forms of arthritis. Limonin (Lim) is extracted from lemons and other citrus fruits. Limonin has …
[HTML][HTML] Oral chromium exposure and toxicity
Abstract Hexavalent chromium [Cr (VI)] is a known carcinogen when inhaled. However,
inhalational exposure to Cr (VI) affects only a small portion of the population, mainly by …
inhalational exposure to Cr (VI) affects only a small portion of the population, mainly by …
Concentration-dependent effects of cobalt and chromium ions on osteoarthritic chondrocytes
C Bauer, C Stotter, V Jeyakumar… - Cartilage, 2021 - journals.sagepub.com
Objective Cobalt and chromium (CoCr) ions from metal implants are released into the joint
due to biotribocorrosion, inducing apoptosis and altering gene expression in various cell …
due to biotribocorrosion, inducing apoptosis and altering gene expression in various cell …