Genetic basis for metronidazole and clarithromycin resistance in Helicobacter pylori strains isolated from patients with gastroduodenal disorders

SJ Hashemi, AF Sheikh, H Goodarzi… - Infection and Drug …, 2019 - Taylor & Francis
Background The aim of this study was to evaluate the antimicrobial resistance and genetic
basis for metronidazole (Mtz) and clarithromycin (Cla) resistance in strains of Helicobacter …

Mutations of Helicobacter pylori RdxA are mainly related to the phylogenetic origin of the strain and not to metronidazole resistance

S Zhang, X Wang, MJ Wise, Y He… - Journal of …, 2020 - academic.oup.com
Abstract Objectives Drug resistance of Helicobacter pylori is a major clinical problem
worldwide. The objective of the present study was to investigate the prevalence of antibiotic …

RdxA Diversity and Mutations Associated with Metronidazole Resistance of Helicobacter pylori

Y Gong, K Zhai, L Sun, L He, H Wang, Y Guo… - Microbiology …, 2023 - Am Soc Microbiol
Metronidazole (MNZ) is administered as first-line antibiotic for Helicobacter pylori
eradication therapy; however, increasing resistance to MNZ impaired the efficacy. Increasing …

High Prevalence of Antibiotic Resistance in Iranian Helicobacter pylori Isolates: Importance of Functional and Mutational Analysis of Resistance Genes and Virulence …

N Farzi, A Yadegar, A Sadeghi… - Journal of clinical …, 2019 - mdpi.com
The high prevalence of antibiotic resistance in Helicobacter pylori has become a great
challenge in Iran. The genetic mutations that contribute to the resistance have yet to be …

[HTML][HTML] Helicobacter pylori antibiotic resistance in Iran

M Mohammadi, D Doroud, N Mohajerani… - World journal of …, 2005 - ncbi.nlm.nih.gov
AIM: To examine the frequency of antibiotic resistance in Iranian Helicobacter pylori (H
pylori) strains isolated from two major hospitals in Tehran. METHODS: Examination of …

Genotype profiles of Helicobacter pylori from gastric biopsies and strains with antimicrobial-induced resistance

Y Wang, F Wang, X Gong, L Yan… - Therapeutic …, 2020 - journals.sagepub.com
Background and aims: The genotypic method could significantly shorten the time needed to
obtain antibiotic susceptibility data for Helicobacter pylori. The aim of this study was to …

Phenotype and genotype analysis for Helicobacter pylori antibiotic resistance in outpatients: a retrospective study

M Xiong, HS Mohammed Aljaberi… - Microbiology …, 2023 - Am Soc Microbiol
To investigate the antibiotic resistance of Helicobacter pylori (H. pylori) in outpatients and to
explore the consistency between genotype and phenotype of H. pylori antibiotic resistance …

Mutations Related to Antibiotics Resistance in Helicobacter pylori Clinical Isolates from Bangladesh

KA Fauzia, H Aftab, E Tshibangu-Kabamba, RI Alfaray… - Antibiotics, 2023 - mdpi.com
Current management of gastric inflammation involves the eradication of Helicobacter pylori.
However, the effectiveness of commonly used antibiotics against H. pylori infection has …

In vitro induction of resistance to metronidazole, and analysis of mutations in rdxA and frxA genes from Helicobacter pylori isolates

LP Aldana, M Kato, T Kondo, S Nakagawa… - Journal of infection and …, 2005 - Springer
In clinical Helicobacter pylori isolates, metronidazole resistance has been associated with
mutations in the rdxA and frxA genes. The aim of this study was to examine the role of the …

[HTML][HTML] The mutation of the rdxA gene in metronidazole-resistant Helicobacter pylori clinical isolates

N Mirzaei, F Poursina, S Moghim… - Advanced biomedical …, 2014 - journals.lww.com
Objective: This study is trying to describe the mutational mechanisms of metronidazole
resistance in H. pylori in our clinical isolates in Isfahanian patients, Iran and compare with …