Kaposi's sarcoma–associated herpesvirus encodes a chemokine called vMIP-II. This protein
displayed a broader spectrum of receptor activities than any mammalian chemokine as it …

The Kaposi's sarcoma–related herpesvirus (KSHV), also designated human herpesvirus 8,
is the presumed etiologic agent of Kaposi's sarcoma and certain lymphomas. Although …

The viral macrophage inflammatory protein-II (vMIP-II) encoded by Kaposi's sarcoma-
associated herpesvirus is unique among all known chemokines in that vMIP-II shows a …

Unique among known human herpesviruses, Kaposi's sarcoma–associated herpesvirus
(KSHV or HHV-8) encodes chemokine-like proteins (vMIP-I and vMIP-II). vMIP-II was shown …

Kaposi's sarcoma-associated herpesvirus (KSHV) encodes 3 genes that are homologous to
cellular chemokines. vMIP-III, the product of open reading frame K4. 1, is the most distantly …

Four virus proteins similar to two human macrophage inflammatory protein (MIP)
chemokines, interleukin-6 (IL-6), and interferon regulatory factor (IRF) are encoded by the …

Uncertainty regarding viral chemokine function is mirrored by an incomplete knowledge of
host chemokine receptor usage by the virally encoded proteins. One such molecule is vMIP …

Kaposi's sarcoma (KS) lesions are characterized by a prominent leukocyte infiltrate
composed of mononuclear phagocytes and T cells. KS-associated CD4+ and CD8+ cells …

Chemokines are a family of small proteins that interact with seven-transmembrane domain
receptors and modulate the migration of immune cells into sites of inflammation and …

Human herpesvirus 8 (HHV-8) is a recently discovered virus that is highly associated with
Kaposi's sarcoma (KS) and AIDS-associated body cavity lymphomas, although it is also …