Polymyxins interaction to the human serum albumin: A thermodynamic and computational study

A Poursoleiman, MH Karimi-Jafari… - … Acta Part A: Molecular …, 2019 - Elsevier
Polymyxin B and E (colistin), are a group of cationic charged cyclic antibiotic lipopeptides
that are frequently used in the clinics to treat infections caused by the multidrug-resistant …

Structure–activity relationships for the binding of polymyxins with human α-1-acid glycoprotein

MAK Azad, JX Huang, MA Cooper, KD Roberts… - Biochemical …, 2012 - Elsevier
Here, for the first time, we have characterized binding properties of the polymyxin class of
antibiotics for human α-1-acid glycoprotein (AGP) using a combination of biophysical …

Lipid binding and membrane penetration of polymyxin B derivatives studied in a biomimetic vesicle system

M Katz, H Tsubery, S Kolusheva, A Shames… - Biochemical …, 2003 - portlandpress.com
Understanding membrane interactions and cell-wall permeation of Gram-negative bacteria
is of great importance, owing to increasing bacterial resistance to existing drugs and …

Characterization of the myricetin− human serum albumin complex by spectroscopic and molecular modeling approaches

C Qin, MX Xie, Y Liu - Biomacromolecules, 2007 - ACS Publications
The interaction mechanism of flavonol myricetin (3, 5, 7, 3 ', 4 ', 5 '-hexahydroxyflavone) and
human serum albumin (HSA) has been characterized by fluorescence, electronic …

Mechanistic and conformational studies on the interaction between myriocin and human serum albumin by fluorescence spectroscopy and molecular docking

M Zhang, Y Chai, B Han - Journal of Solution Chemistry, 2019 - Springer
The interactions between myriocin (ISP-1) and human serum albumin (HSA) were studied
by fluorescence spectroscopy, synchronous fluorescence spectroscopy, three-dimensional …

Investigating the effect of pH on the interaction of cypermethrin with human serum albumin: Insights from spectroscopic and molecular dynamics simulation studies

MA Mohammadi, B Shareghi, S Farhadian… - International Journal of …, 2024 - Elsevier
To efficiently combat the negative consequences of the utilization of pesticides and
hazardous substances with biomolecules, it is crucial to comprehend the features of the …

Insight into the binding mechanism of imipenem to human serum albumin by spectroscopic and computational approaches

MT Rehman, H Shamsi, AU Khan - Molecular Pharmaceutics, 2014 - ACS Publications
The mechanism of interaction between imipenem and HSA was investigated by various
techniques like fluorescence, UV–vis absorbance, FRET, circular dichroism, urea …

Interaction between phillygenin and human serum albumin based on spectroscopic and molecular docking

W Song, MZ Ao, Y Shi, LF Yuan, XX Yuan… - Spectrochimica Acta Part …, 2012 - Elsevier
In this paper, the interaction of human serum albumin (HSA) with phillygenin was
investigated by fluorescence, circular dichroism (CD), UV–vis spectroscopic and molecular …

[HTML][HTML] Research on the Interaction Mechanism and Structural Changes in Human Serum Albumin with Hispidin Using Spectroscopy and Molecular Docking

SH Fan, WQ Wang, YW Zhou, XJ Gao, Q Zhang… - Molecules, 2024 - mdpi.com
The interaction between human serum albumin (HSA) and hispidin, a polyketide abundantly
present in both edible and therapeutic mushrooms, was explored through multispectral …

Biophysical characterization of polymyxin B interaction with LPS aggregates and membrane model systems

MM Domingues, RG Inácio, JM Raimundo… - Peptide …, 2012 - Wiley Online Library
Antibiotic resistance is an increasingly severe health problem. Antimicrobial peptides
(AMPs) are being developed in order to overcome this problem, due to their lower bacterial …