The transcriptional coactivator p300/CBP (CREBBP) is a histone acetyltransferase (HAT)
that regulates gene expression by acetylating histones and other transcription factors …

Histone acetylation is important in chromatin remodelling and gene activation,,,. Nearly all
known histone-acetyltransferase (HAT)-associated transcriptional co-activators contain …

The transcriptional coactivator p300 is a histone acetyltransferase (HAT) whose function is
critical for regulating gene expression in mammalian cells. However, the molecular events …

The dynamic and reversible acetylation of proteins, catalysed by histone acetyltransferases
(HATs) and histone deacetylases (HDACs), is a major epigenetic regulatory mechanism of …

The histone acetyl transferases CREB-binding protein (CBP) and its paralog p300 play a
critical role in numerous cellular processes. Dysregulation of their catalytic activity is …

A number of transcriptional coactivators possess intrinsic histone acetylase activity,
providing a direct link between hyperacetylated chromatin and transcriptional activation. We …

Abstract p300/CBP is a transcriptional adaptor that integrates signals from many sequence-
specific activators via direct interactions. Various cellular and viral factors target p300/CBP to …

CBP and p300 are histone acetyltransferases (HATs) that associate with and acetylate
transcriptional regulators and chromatin. Mutations in their catalytic'cores' are linked to …

The transcriptional co-activator p300 is a histone acetyltransferase (HAT) that is typically
recruited to transcriptional enhancers and regulates gene expression by acetylating …

Protein lysine acetyltransferases (HATs or PATs) acetylate histones and other proteins, and
are principally modeled as transcriptional coactivators. CREB binding protein (CBP …