Development of remote stimulation techniques for neuronal tissues represents a challenging
goal. Among the potential methods, mechanical stimuli are the most promising vectors to …

Externally controlling the excitation of a neuronal subset through ion channels activation can
modulate the firing pattern of an entire neural circuit in vivo. As nanovalves in the cell …

Mechanosensory transduction is defined as the ability of living cells to respond to a wide
variety of mechanical stimuli and convert them into electrical and/or biochemical intracellular …

Publisher Summary This chapter discusses mechanosensitive (MS) ion channels in
eukaryotic cells. MS channels are ubiquitous, abundant, and diverse. The chapter also …

Cells respond to a wide variety of mechanical stimuli, ranging from thermal molecular
agitation to potentially destructive cell swelling caused by osmotic pressure gradients. The …

Mechanosensitive ion channels are a class of ion channels which transduce mechanical
forces of the cell membrane into an electrical response. These channels are gated by the …

Little is known of molecular mechanisms of human mechanosensation. Only now are
candidate eukaryotic sensors being identified. In contrast, bacterial sensors, including …

abstract What are the stimuli that are sensed by mechanoreceptors? Researchers have now
begun to address this question and determine the molecular mechanisms underlying …

Mechanosensitive ion channels are gated directly by physical stimuli and transduce these
stimuli into electrical signals. Several criteria must apply for a channel to be considered …

Mechanosensitivity is a universal property of cells and provides an obvious survival
advantage for free living organisms who must back away from barriers and evade predators …