The therapeutic efficacy of anthracyclines relies on antitumor immune responses elicited by
dying cancer cells. How chemotherapy-induced cell death leads to efficient antigen …

Immunogenic cell death is characterized by the early surface exposure of chaperones
including calreticulin and HSPs, which affect dendritic cell (DC) maturation and the uptake …

The therapeutic efficacy of anthracyclines relies, at least partially, on the induction of a
dendritic cell–and T-lymphocyte–dependent anticancer immune response. Here, we show …

Anthracyclines are a class of drugs, including doxorubicin, epirubicin and idarubicin, used in
cancer chemotherapy which are derived from Streptomyces bacterium Streptomyces …

We show, in a series of established experimental breast adenocarcinomas and
fibrosarcomas induced by carcinogen de novo in mice, that the therapeutic efficacy of …

The way a tumor cell dies is believed to influence both its engulfment by dendritic cells (DC)
and access of the relevant antigen (s) to the cross-presentation pathway. Here we have …

Certain chemotherapeutic regimens trigger cancer cell death while inducing dendritic cell
maturation and subsequent immune responses. However, chemotherapy‐induced …

Dendritic cells (DCs) are essential for the induction of adaptive immune responses against
malignant cells by virtue of their capacity to effectively cross-present exogenous antigens to …

Systemic anticancer chemotherapy is immunosuppressive and mostly induces
nonimmunogenic tumor cell death. Here, we show that even in the absence of any adjuvant …

The expansion of immunosuppressive cells represents a cardinal strategy deployed by
tumors to escape from detection and elimination by the immune system. Regulatory T …