Targeted microbubble imaging at ultrasound frequencies above 5 MHz has applications in
both a preclinical context for a range of disease processes and clinically for the assessment …

Targeted microbubbles detected with high-frequency ultrasound can establish the molecular
expression of blood vessels with submillimeter resolution. To improve microbubble-specific …

There are a range of contrast ultrasound applications above 10 MHz, a frequency regime in
which nonlinear microbubble behavior is poorly understood. Lipid-encapsulated …

Objective The sensitivity of the acoustic response of microbubbles, specifically a strong
correlation between their subharmonic response and the ambient pressure, has motivated …

One of the main challenges for ultrasound molecular imaging is acoustically distinguishing
nonbound microbubbles from those bound to their molecular target. In this in vitro study, we …

The response of encapsulated microbubbles at half the ultrasound insonation frequency,
termed subharmonic response, may have potential applications in diagnosis and therapy …

Subharmonic signals backscattered from gas-filled lipid-shelled microbubbles have
generated significant research interest because they can improve the detection and …

Ultrasound molecular imaging utilizes targeted microbubbles to bind to vascular targets
such as integrins, selectins and other extracellular binding domains. After binding, these …

Acoustic angiography imaging of microbubble contrast agents uses the superharmonic
energy produced from excited microbubbles and enables high-contrast, high-resolution …

A linear relationship between the relative expansion of an off-resonance ultrasound contrast
microbubble and low acoustic pressures is expected. In this study, high-speed optical …