Identifying some theories in developmental biology: The case of the cancer stem cell theory

L Laplane - Minelli and Pradeu (2014b), 2014 - books.google.com
To know whether there are theories of development in developmental biology, one will need
to know how to recognize them. This is, in fact, far from a trivial task. Biologists use the …

Stem cell epistemological issues

L Laplane - Stem cell biology and regenerative medicine, 2022 - taylorfrancis.com
This chapter brings a philosophical perspective to the concept of stem cell. Three general
questions both clarify the concept of stem cell and emphasize its ambiguities:(1) How should …

Stem cell conceptual clarifications

L Laplane - Stem Cell Biology and Regenerative Medicine, 2022 - api.taylorfrancis.com
Everybody knows what a stem cell is, and yet nobody knows what a stem cell is. Stem cells
are traditionally characterized by two functional properties: self-renewal and differentiation …

Regenerating theories in developmental biology

T Pradeu - Minelli and Pradeu (2014b), 2014 - books.google.com
Developmental biology offers descriptions and explanations of the processes involved in the
development of living entities. But does it formulate theories? If it does not, does this raise …

What is the nature of stem cells? A unified dispositional framework

J Suárez - Biology & Philosophy, 2023 - Springer
This paper presents an account of the nature of stem cells based on the philosophical
concept of disposition. It is argued that stem cells can be conceived as dispositional objects …

Stem cell lineages: between cell and organism

MB Fagan - Philosophy, Theory, and Practice in Biology, 2017 - philsci-archive.pitt.edu
Ontologies of living things are increasingly grounded on the concepts and practices of
current life science. Biological development is a process, undergone by living things, which …

[图书][B] Cancer stem cells: philosophy and therapies

L Laplane - 2016 - books.google.com
An innovative theory proposes a new therapeutic strategy to break the stalemate in the war
on cancer. It is called cancer stem cell (CSC) theory, and Lucie Laplane offers a …

Towards a classification of stem cells

L Laplane, E Solary - Elife, 2019 - elifesciences.org
The characteristic properties of stem cells–notably their ability to self-renew and to
differentiate–have meant that they have traditionally been viewed as distinct from most other …

On the structure of biological explanations: Beyond functional ascriptions in cancer research

M Bertolaso - Epistemologia: rivista italiana di filosofia della scienza …, 2013 - torrossa.com
The aim of this paper is to assess the relevance of functional ascriptions used to explain
cancer. I do that in two steps. In the first part of the paper I briefly analyse different functional …

Hierarchies and causal relationships in interpretative models of the neoplastic process

M Bertolaso - History and philosophy of the life sciences, 2011 - JSTOR
The aim of this paper is to present a critical analysis of the kind of biological systems
identified in the main explanatory theories of cancer (ie Somatic Mutation Theory and Tissue …