Down‐regulation of microRNA‐34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance

F Niederer, M Trenkmann, C Ospelt… - Arthritis & …, 2012 - Wiley Online Library
Objective To investigate the expression and effect of the microRNA‐34 (miR‐34) family on
apoptosis in rheumatoid arthritis synovial fibroblasts (RASFs). Methods Expression of the …
被引用次数：174 相关文章 所有 11 个版本

Induction of apoptosis in the synovium of mice with autoantibody‐mediated arthritis by the intraarticular injection of double‐stranded MicroRNA‐15a

Y Nagata, T Nakasa, Y Mochizuki… - Arthritis & …, 2009 - Wiley Online Library
Objective MicroRNA is a family of noncoding RNAs that exhibit tissue‐specific or
developmental stage–specific expression patterns and are associated with human diseases …
被引用次数：123 相关文章 所有 7 个版本
[PDF] spandidos-publications.com

miR-143-3p regulates cell proliferation and apoptosis by targeting IGF1R and IGFBP5 and regulating the Ras/p38 MAPK signaling pathway in rheumatoid arthritis

Z Yang, J Wang, Z Pan… - Experimental and …, 2018 - spandidos-publications.com
It has been demonstrated that the deregulation of microRNAs (miRNAs) affects the
development of rheumatoid arthritis (RA). The primary objective of the current study was to …
被引用次数：57 相关文章 所有 11 个版本
[PDF] spandidos-publications.com

Downregulation of microRNA‑221 decreases migration and invasion in fibroblast‑like synoviocytes in rheumatoid arthritis

S Yang, Y Yang - Molecular Medicine Reports, 2015 - spandidos-publications.com
MicroRNAs (miRNAs/miRs) are a group of non‑coding RNAs that regulate the activity of
target mRNAs and cellular processes, and which have been implicated in the pathogenesis …
被引用次数：84 相关文章 所有 10 个版本

Up-regulation of miR-365 promotes the apoptosis and restrains proliferation of synoviocytes through downregulation of IGF1 and the inactivation of the PI3K/AKT …

X Wang, S Gong, D Pu, N Hu, Y Wang, P Fan… - International …, 2020 - Elsevier
Background There is growing evidence of the ability of microRNAs (miRs) in rheumatoid
arthritis (RA), thus our objective was to discuss the impact of miR-365 on the apoptosis and …
被引用次数：29 相关文章 所有 3 个版本
[PDF] oup.com

Silencing microRNA-34a inhibits chondrocyte apoptosis in a rat osteoarthritis model in vitro

MM Abouheif, T Nakasa, H Shibuya, T Niimoto… - …, 2010 - academic.oup.com
Objective. miRNAs, which are non-coding RNAs, play a role in the pathogenesis of disease
including OA. miRNA (miR)-34a is induced by p53, subsequently leading to cell apoptosis …
被引用次数：190 相关文章 所有 10 个版本
[HTML] nih.gov

[HTML][HTML] MicroRNA-126 affects rheumatoid arthritis synovial fibroblast proliferation and apoptosis by targeting PIK3R2 and regulating PI3K-AKT signal pathway

Y Qu, J Wu, JX Deng, YP Zhang, WY Liang, ZL Jiang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes inflammation and
destruction of the joints as well as an increased risk of cardiovascular disease. RA synovial …
被引用次数：60 相关文章 所有 7 个版本
[PDF] wiley.comFull View

MicroRNA‐21 Promotes Proliferation of Fibroblast‐Like Synoviocytes through Mediation of NF‐κB Nuclear Translocation in a Rat Model of Collagen‐Induced …

Y Chen, PF Xian, L Yang… - BioMed research …, 2016 - Wiley Online Library
MicroRNA‐21 (miR‐21) is overexpressed in patients with rheumatoid arthritis (RA). This
study was designed to investigate the effect and mechanism of miR‐21 on cell proliferation …
被引用次数：49 相关文章 所有 10 个版本
[HTML] nih.gov

[HTML][HTML] Expression and function of microRNA-188-5p in activated rheumatoid arthritis synovial fibroblasts

A Ruedel, P Dietrich, T Schubert… - … Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
Activated synovial fibroblasts in rheumatoid arthritis (RASF) play a critical role in the
pathology of rheumatoid arthritis (RA). Recent studies suggested that deregulation of …
被引用次数：42 相关文章 所有 9 个版本
[HTML] nih.gov

Altered expression of microRNA‐203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation

J Stanczyk, C Ospelt, E Karouzakis, A Filer… - Arthritis & …, 2011 - Wiley Online Library
Objective MicroRNA (miRNA) are recognized as important regulators of a variety of
fundamental biologic processes. Previously, we described increased expression of miR‐155 …
被引用次数：386 相关文章 所有 21 个版本