Hematopoiesis is the process by which a limited number of hematopoietic stem cells (HSCs)
maintain a functioning blood and immune system. In adults, hematopoiesis occurs in bone …

Originally discovered in the 1930s, tachykinins have been a subject of renewed interest.
Antagonists to the tachykinin receptors have shown potential in the treatment of a variety of …

Introduction: hematopoiesis: an overview 3. Neuroendocrine-immune-hematopoietic axis
3.1. Tachykinins: brief overview 3.2. Neurokinin (NK) receptors 3.3. Tachykinins in …

[Frontiers in Bioscience 9, 3331-3332, September 1, 2004] 3331 TACHYKININ-MEDIATED
MODULATION OF THE IMMUNE RESPONSE Kenneth L. Page 1 [Frontiers in Bioscience 9 …

Abstract Hemokinin-1 (HK-1), encoded by the TAC4 gene, is a tachykinin peptide that is
predominantly expressed in non-neuronal cells, such as immune cells. We have disrupted …

Tachykinins are a large group of neuropeptides with both central and peripheral activity.
Despite the increasing number of studies reporting a growth supportive effect of tachykinin …

We have been studying hematopoietic effects by the tachykinins, which like many other
neuropeptides can be expressed in neural and nonneural tissues. Substance P (SP) and …

Abstract Hemokinin 1 (HK-1) is a new member of the tachykinin peptide family that is
expressed in hematopoietic cells. Recent reports studying mouse, rat, and human orthologs …

Hematopoiesis is the process by which immune and blood cells are produced from a finite
number of relatively few hematopoietic stem cells (HSCs). In adults, hematopoiesis occurs in …

We report here the molecular cloning of a newly identified preprotachykinin gene, Pptc,
which specifies the sequence for a new preprotachykinin protein and bioactive peptide …