Antimicrobial peptides (AMPs) provide a promising solution to the serious threat of multidrug-
resistant bacteria or superbugs to public healthcare, due to their unique disruption to …

Antimicrobial peptides (AMPs), as a key component of the immune defense systems of
organisms, are a promising solution to the serious threat of drug-resistant bacteria to public …

The membrane disruption and pore-forming mechanism of melittin has been widely
explored by experiments and computational studies. However, the precise mechanism is still …

Most antimicrobial peptides exert their activity by interacting with bacterial membranes, thus
perturbing their permeability. They are investigated as a possible solution to the insurgence …

Many fundamental biological processes occur on cell membranes, and a typical example is
the membrane permeabilization by peptides for an antimicrobial purpose. Previous studies …

The antimicrobial peptide, melittin, is a potential next-generation antibiotic because melittin
can spontaneously form pores in bacterial cell membranes and cause cytoplasm leakage …

The prototypical antimicrobial peptide, melittin, is well-known for its ability to induce pores in
zwitterionic model lipid membranes. However, the mechanism by which melittin …

Membrane-active peptides (MAPs) are able to induce pores in cell membranes via
molecular mechanisms, which are still subject to ongoing research. In this work, we present …

The exploitation of conventional antibiotics in conjunction with the adeptness of microbes
has led to the emergence of multi-drug-resistant pathogens. This has posed a severe threat …

Antimicrobial peptides (AMPs) represent a promising class of compounds to fight resistant
infections. They are commonly thought to kill bacteria by perturbing the permeability of their …