Age and sex are major risk factors in Alzheimer's disease (AD) with a higher incidence of the
disease in females. Neuroinflammation, which is a hallmark of AD, contributes to disease …

Females show a disproportionate burden of Alzheimer's disease pathology and higher
Alzheimer's disease dementia prevalences compared to males, yet the mechanisms driving …

One area of microglial biology that has been relatively neglected until recently is sex
differences and this is in spite of the fact that sex is a risk factor in several diseases that are …

Background In vivo assessment of neuroinflammation by 18-kDa translocator protein
positron-emission-tomography (TSPO-PET) ligands receives growing interest in preclinical …

Alzheimer's disease (AD) is the most common form of dementia among the elderly,
characterized by parenchymal and vascular beta-amyloid (Aβ) burden, tau pathology …

Microglia dysfunction and activation are important hallmarks of the aging brain and are
concomitant with age‐related neurodegeneration and cognitive decline. Age‐associated …

Alzheimer's disease (AD) and the mechanisms underlying its etiology and progression are
complex and multifactorial. The higher AD risk in women may serve as a clue to better …

Sex differences in the manifestations of Alzheimer's disease are under intense investigation.
Despite the emerging importance of polygenic predictions for Alzheimer's disease, sex …

Despite recent advances in the understanding of clinical aspects of sex differences in
Alzheimer's disease (AD), the underlying mechanisms, for instance, how sex modifies AD …

Sex differences have been clinically documented in numerous neurodegenerative diseases
and yet the reasons for these differences are not well understood. Recent studies have …