Expression systems and species used for transgenic animal bioreactors
Y Wang, S Zhao, L Bai, J Fan… - BioMed Research …, 2013 - Wiley Online Library
Transgenic animal bioreactors can produce therapeutic proteins with high value for
pharmaceutical use. In this paper, we compared different systems capable of producing …
pharmaceutical use. In this paper, we compared different systems capable of producing …
Transgenic bioreactors
J Jänne, L Alhonen, JM Hyttinen, T Peura… - Biotechnology Annual …, 1998 - Elsevier
Since the generation of the first transgenic mice in 1980, transgene technology has also
been successfully applied to large farm animals. Although this technology can be employed …
been successfully applied to large farm animals. Although this technology can be employed …
The transgenic animal platform for biopharmaceutical production
LR Bertolini, H Meade, CR Lazzarotto, LT Martins… - Transgenic …, 2016 - Springer
The recombinant production of therapeutic proteins for human diseases is currently the
largest source of innovation in the pharmaceutical industry. The market growth has been the …
largest source of innovation in the pharmaceutical industry. The market growth has been the …
Transgenic bioreactors
J Jänne, JM Hyttinen, T Peura, M Tolvanen… - International journal of …, 1994 - Elsevier
1. Although many human therapeutic proteins are currently produced in microbial fermentors
using recombinant DNA techniques, it is obvious that microbial processing is not suitable for …
using recombinant DNA techniques, it is obvious that microbial processing is not suitable for …
Making recombinant proteins in animals–different systems, different applications
Transgenic animal bioreactors represent a powerful tool to address the growing need for
therapeutic recombinant proteins. The ability of transgenic animals to produce complex …
therapeutic recombinant proteins. The ability of transgenic animals to produce complex …
[HTML][HTML] Transgenic animal bioreactors
LM Houdebine - Transgenic research, 2000 - Springer
The production of recombinant proteins is one of the major successes of biotechnology.
Animal cells are required to synthesize proteins with the appropriate post-translational …
Animal cells are required to synthesize proteins with the appropriate post-translational …
Biotechnology for the production of modified and innovative animal products: transgenic livestock bioreactors
RJ Wall - Livestock Production Science, 1999 - Elsevier
The ability to modify mammary gland function through genetic engineering provides an
opportunity to investigate mechanism of breast cancer, enhance the nutritional quality of milk …
opportunity to investigate mechanism of breast cancer, enhance the nutritional quality of milk …
Production of bioproducts through the use of transgenic animal models
CL Keefer - Animal Reproduction Science, 2004 - Elsevier
Transgenic livestock that produce recombinant proteins in their milk can provide an
economic and safe system for production of valuable proteins, such as pharmaceutical …
economic and safe system for production of valuable proteins, such as pharmaceutical …
Transgenic animals: beyond 'funny milk'
JS Logan - Current Opinion in Biotechnology, 1993 - Elsevier
The expression of therapeutically useful proteins in transgenic animals is a field of
biotechnology that is now coming of age. Over the past few years, significant progress has …
biotechnology that is now coming of age. Over the past few years, significant progress has …
Transgenic rabbits as bioreactors for the production of human growth hormone
JM Limonta, FO Castro, R Martínez, P Puentes… - Journal of …, 1995 - Elsevier
Gene fanning is one of the most promising areas in modern biotechnology. To assay the
potential usefulness of transgenic rabbits as bioreactors, one cell embryos were …
potential usefulness of transgenic rabbits as bioreactors, one cell embryos were …