[HTML][HTML] Delineating biological and technical variance in single cell expression data
Single cell transcriptomics is becoming a common technique to unravel new biological
phenomena whose functional significance can only be understood in the light of differences …
phenomena whose functional significance can only be understood in the light of differences …
The added value of single-cell gene expression profiling
A Ståhlberg, V Rusnakova… - Briefings in functional …, 2013 - academic.oup.com
Cells are the basic unit of life and they have remarkable abilities to respond individually as
well as in concert to internal and external stimuli in a specific manner. Studying complex …
well as in concert to internal and external stimuli in a specific manner. Studying complex …
A brief review of single-cell transcriptomic technologies
T Kalisky, S Oriel, TH Bar-Lev… - Briefings in …, 2018 - academic.oup.com
In recent years, there has been an effort to develop new technologies for measuring gene
expression and sequence information from thousands of individual cells. Large data sets …
expression and sequence information from thousands of individual cells. Large data sets …
[HTML][HTML] Single cells make big data: new challenges and opportunities in transcriptomics
Recent technological advances have enabled unprecedented insight into transcriptomics at
the level of single cells. Single cell transcriptomics enables the measurement of …
the level of single cells. Single cell transcriptomics enables the measurement of …
Single-cell sequencing leads a new era of profiling transcriptomic landscape
H Zhang, N Cui, Y Cai, F Lei… - Journal of Bio-X Research, 2018 - journals.lww.com
Understanding the complexity of biological systems requires a comprehensive analysis of
their cell populations. Ideally, this should be done at the single cell level, because bulk …
their cell populations. Ideally, this should be done at the single cell level, because bulk …
Single cell transcriptomics comes of age
S Aldridge, SA Teichmann - Nature communications, 2020 - nature.com
Single cell transcriptomics technologies have vast potential in advancing our understanding
of biology and disease. Here, Sarah Aldridge and Sarah Teichmann review the last decade …
of biology and disease. Here, Sarah Aldridge and Sarah Teichmann review the last decade …
Computational approaches for high‐throughput single‐cell data analysis
H Todorov, Y Saeys - The FEBS journal, 2019 - Wiley Online Library
During the past decade, the number of novel technologies to interrogate biological systems
at the single‐cell level has skyrocketed. Numerous approaches for measuring the proteome …
at the single‐cell level has skyrocketed. Numerous approaches for measuring the proteome …
cgCorrect: a method to correct for confounding cell–cell variation due to cell growth in single-cell transcriptomics
Accessing gene expression at a single-cell level has unraveled often large heterogeneity
among seemingly homogeneous cells, which remains obscured when using traditional …
among seemingly homogeneous cells, which remains obscured when using traditional …
[HTML][HTML] Algorithmic advances in machine learning for single-cell expression analysis
Numerous recent insights into the complex and dynamic cellular signatures of biological
function, development and disease are owed to technical advances in single cell …
function, development and disease are owed to technical advances in single cell …
Big data analytics in single‐cell transcriptomics: Five grand opportunities
Single‐cell omics technologies provide biologists with a new dimension for systematically
dissecting the underlying complexities within biological systems. These powerful …
dissecting the underlying complexities within biological systems. These powerful …