[HTML][HTML] Myeloid type I interferon signaling promotes atherosclerosis by stimulating macrophage recruitment to lesions
P Goossens, MJJ Gijbels, A Zernecke, W Eijgelaar… - Cell metabolism, 2010 - cell.com
Inflammatory cytokines are well-recognized mediators of atherosclerosis. Depending on the
pathological context, type I interferons (IFNs; IFNα and IFNβ) exert either pro-or anti …
pathological context, type I interferons (IFNs; IFNα and IFNβ) exert either pro-or anti …
Interferons as essential modulators of atherosclerosis
MCS Boshuizen, MPJ de Winther - … , thrombosis, and vascular …, 2015 - Am Heart Assoc
Interferons (IFNs) are key regulators of both innate and adaptive immune responses. The
family of IFN cytokines can be divided into 3 main subtypes of which type I and type II IFNs …
family of IFN cytokines can be divided into 3 main subtypes of which type I and type II IFNs …
Interferon-γ and atherosclerosis: pro-or anti-atherogenic?
EJ Harvey, DP Ramji - Cardiovascular research, 2005 - academic.oup.com
Atherosclerosis is considered to be a form of chronic inflammation governed by a complex
network of inter-and intra-cellular signaling pathways. The pleiotropic cytokine interferon-γ …
network of inter-and intra-cellular signaling pathways. The pleiotropic cytokine interferon-γ …
Type-I interferons in atherosclerosis
The contribution of dyslipidemia and inflammation in atherosclerosis is well established.
Along with effective lipid-lowering treatments, the recent success of clinical trials with anti …
Along with effective lipid-lowering treatments, the recent success of clinical trials with anti …
Atherosclerosis and interferon-γ: new insights and therapeutic targets
I Voloshyna, MJ Littlefield, AB Reiss - Trends in cardiovascular medicine, 2014 - Elsevier
Atherosclerosis is considered to be a chronic inflammatory disease of the arterial wall.
Atherogenesis is accompanied by local production and release of inflammatory mediators …
Atherogenesis is accompanied by local production and release of inflammatory mediators …
The role of interferon-γ in cardiovascular disease: an update
A Elyasi, I Voloshyna, S Ahmed, LJ Kasselman… - Inflammation …, 2020 - Springer
Purpose Cardiovascular disease (CVD) is the leading cause of death, globally, and its
prevalence is only expected to rise due to the increasing incidence of co-morbidities such as …
prevalence is only expected to rise due to the increasing incidence of co-morbidities such as …
Interferon gamma: a master regulator of atherosclerosis
JE McLaren, DP Ramji - Cytokine & growth factor reviews, 2009 - Elsevier
Atherosclerosis is a chronic inflammatory disease that is characterized by the development
of fibrotic plaques in the arterial wall. The disease exhibits a complex aetiology and its …
of fibrotic plaques in the arterial wall. The disease exhibits a complex aetiology and its …
The myeloid type I interferon response to myocardial infarction begins in bone marrow and is regulated by Nrf2-activated macrophages
DM Calcagno, RP Ng Jr, A Toomu, C Zhang… - Science …, 2020 - science.org
Sterile tissue injury is thought to locally activate innate immune responses via damage-
associated molecular patterns (DAMPs). Whether innate immune pathways are remotely …
associated molecular patterns (DAMPs). Whether innate immune pathways are remotely …
Gamma interferon: a central mediator in atherosclerosis
MLA Leon, SH Zuckerman - Inflammation research, 2005 - Springer
Atherosclerosis is a chronic inflammatory disease of the vasculature with lesions developing
in the arterial wall, frequently in the coronary and carotid arteries. The interaction between …
in the arterial wall, frequently in the coronary and carotid arteries. The interaction between …
[HTML][HTML] Interferon-γ: Promising therapeutic target in atherosclerosis
Atherosclerosis is a chronic inflammatory disorder of the vasculature and is the primary
cause of cardiovascular disease (CVD). CVD is currently the world's leading cause of death …
cause of cardiovascular disease (CVD). CVD is currently the world's leading cause of death …