Mouse NK cells express at least seven inhibitory Ly49 receptors. Here we employ a
semiquantitative cell–cell adhesion assay as well as class I/peptide tetramers to provide a …

Mouse NK cells express MHC class I‐specific inhibitory Ly49 receptors. Since these
receptors display distinct ligand specificities and are clonally distributed, their expression …

Abstract The Ly49A NK cell receptor interacts with MHC class I (MHC-I) molecules on target
cells and negatively regulates NK cell-mediated target cell lysis. We have recently shown …

The Ly49 family of NK cell receptors and its MHC-binding characteristics have only been
well characterized in C57BL/6 (B6) mice. Previous studies have shown that 129/J mice …

Members of the murine Ly49 family of receptors have been shown to inhibit and activate NK
cell function. Subsets of Ly49-expressing NK cells mediate the rejection of bone marrow cell …

The Ly‐49 family consists of at least nine members, of which Ly‐49A and C have been
found to be NK‐cell inhibitory receptors specific for class I MHC. The functions of other Ly …

Murine NK cytotoxicity is regulated by two families of MHC class I-specific receptors, namely
Ly49 and CD94/NKG2. We developed a single-cell RT-PCR method to analyze expression …

Murine natural killer (NK) cells are inhibited from killing their targets by the interaction
between inhibitory, C‐type lectin like Ly49 receptors and major histocompatibility complex …

Natural killer cells in the mouse express class 1 MHC‐specific inhibitory receptors of the
Ly49 protein family. The receptors mediate inhibition of the lysis of tumor cells and normal …

The inhibitory receptors for MHC class I have a central role in controlling natural killer (NK)
cell activity. Soon after their discovery, it was found that these receptors have a degree of …