The role of soluble P selectin in the diagnosis of venous thromboembolism
CN Antonopoulos, GS Sfyroeras, JD Kakisis… - Thrombosis research, 2014 - Elsevier
Abstract Introduction Soluble P selectin (sPsel), a member of the selectin family of cell
adhesion receptors, has been proposed as a key molecule in hemostasis and thrombosis …
adhesion receptors, has been proposed as a key molecule in hemostasis and thrombosis …
High concentrations of soluble P-selectin are associated with risk of venous thromboembolism and the P-selectin Thr715 variant
C Ay, LV Jungbauer, T Sailer, T Tengler… - Clinical …, 2007 - academic.oup.com
Background: The cell adhesion molecule P-selectin has an important role in the
pathophysiology of thrombosis. The effect on venous thromboembolism (VTE) of increased …
pathophysiology of thrombosis. The effect on venous thromboembolism (VTE) of increased …
[HTML][HTML] P‐and E‐selectin in venous thrombosis and non‐venous pathologies
M Purdy, A Obi, D Myers, T Wakefield - Journal of Thrombosis and …, 2022 - Elsevier
Venous thromboembolism is a very common and costly health problem worldwide.
Anticoagulant treatment for VTE is imperfect: all have the potential for significant bleeding …
Anticoagulant treatment for VTE is imperfect: all have the potential for significant bleeding …
Evaluation of soluble P-selectin as a marker for the diagnosis of deep venous thrombosis
E Ramacciotti, S Blackburn… - Clinical and Applied …, 2011 - journals.sagepub.com
Objective: The combination of D-dimer and Wells score can exclude, but not confirm, the
diagnosis of deep venous thrombosis (DVT). Since thrombosis and inflammation are …
diagnosis of deep venous thrombosis (DVT). Since thrombosis and inflammation are …
[HTML][HTML] Clinical and genetic correlates of soluble P‐selectin in the community
Background: P‐selectin is a cell adhesion molecule that is involved in atherogenesis, and
soluble concentrations of this biomarker reflect cardiovascular risk. However, the clinical …
soluble concentrations of this biomarker reflect cardiovascular risk. However, the clinical …
P-selectin gene haplotypes modulate soluble P-selectin concentrations and contribute to the risk of venous thromboembolism
C Ay, LV Jungbauer, A Kaider, S Koder… - Thrombosis and …, 2008 - thieme-connect.com
The cell adhesion molecule P-selectin mediates the interaction of activated platelets or
endothelial cells with leukocytes. In arterial and venous thromboembolism (VTE) increased …
endothelial cells with leukocytes. In arterial and venous thromboembolism (VTE) increased …
The emerging value of P-selectin as a disease marker
J Kappelmayer, B Nagy Jr, K Miszti-Blasius… - Clinical Chemistry and …, 2004 - degruyter.com
Activated platelets are key components in many arterial disorders. P-selectin is an activation-
dependent platelet receptor, which is also identified in endothelial cells. Together with E-and …
dependent platelet receptor, which is also identified in endothelial cells. Together with E-and …
The origin of P-selectin as a circulating plasma protein
R Fijnheer, CJM Frijns, J Korteweg… - Thrombosis and …, 1997 - thieme-connect.com
P-selectin is a 140 kD protein found in the α-granules of platelets and the Weibel-Palade
bodies of endothelial cells. On cell activation it is expressed on the cell surface and also …
bodies of endothelial cells. On cell activation it is expressed on the cell surface and also …
High plasma levels of soluble P-selectin are predictive of venous thromboembolism in cancer patients: results from the Vienna Cancer and Thrombosis Study (CATS)
C Ay, R Simanek, R Vormittag… - Blood, The Journal …, 2008 - ashpublications.org
Cancer patients are at high risk for venous thromboembolism (VTE). Laboratory parameters
with a predictive value for VTE could help stratify patients into high-or low-risk groups. The …
with a predictive value for VTE could help stratify patients into high-or low-risk groups. The …
Biomarkers for the diagnosis of venous thromboembolism: D-dimer, thrombin generation, procoagulant phospholipid and soluble P-selectin
Background The diagnostic algorithm for venous thromboembolism (VTE) currently involves
a composite of pre-test probability, D-dimer and imaging. Other laboratory tests, however …
a composite of pre-test probability, D-dimer and imaging. Other laboratory tests, however …
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