This article challenges Speakman's hypothesis that the modern genetic predisposition to
obesity has arisen through random genetic drift in the two million years following predation …

Almost 50 years ago Neel proposed a hypothesis to explain the prevalence of obesity and
diabetes in modern society—the 'thrifty gene'hypothesis. The fundamental basis of the …

The prevalence of obesity in modern societies has two major contributory factors—an
environmental change that has happened in historical times and a genetic predisposition …

Obesity is an escalating threat of pandemic proportions, currently affecting billions of people
worldwide and exerting a devastating socioeconomic influence in industrialized countries …

Human obesity has a large genetic component, yet has many serious negative
consequences. How this state of affairs has evolved has generated wide debate. The thrifty …

The" thrifty gene hypothesis" suggests we evolved genes for efficient food collection and fat
deposition to survive periods of famine and that now that food is continuously available …

Obesity, diabetes, and metabolic syndrome are growing worldwide health concerns, yet their
causes are not fully understood. Research into the etiology of the obesity epidemic is highly …

Over the last 50 years there has been a major epidemic of obesity and associated co-
morbidities, the so-called 'metabolic syndrome', mostly in the western world but with an …

It is hard to dispute the fact that the prevalence of overweight and obesity is increasing
around the world and that the obese are becoming more severely obese. However, there …

Although it appeared relatively suddenly, the current obesity epidemic–largely manifest in
industrialized societies but now spreading to the rest of the world–is the result of interaction …