Nitric oxide in cancer metastasis

H Cheng, L Wang, M Mollica, AT Re, S Wu, L Zuo - Cancer letters, 2014 - Elsevier
Cancer metastasis is the spread and growth of tumor cells from the original neoplasm to
further organs. This review analyzes the role of nitric oxide (NO radical dot), a signaling …

Nitric oxide and metastatic cell behaviour

EL Williams, MBA Djamgoz - Bioessays, 2005 - Wiley Online Library
Nitric oxide (NO) is a pleiotropic signalling molecule that subserves a wide variety of basic
cellular functions and also manifests itself pathophysiologically. As regards cancer and its …

Role of nitric oxide in tumor progression: lessons from experimental tumors

PK Lala, A Orucevic - Cancer and Metastasis Reviews, 1998 - Springer
Nitric oxide (NO), a potent biological mediator, plays a key role in physiological as well as
pathological processes, including inflammation and cancer. The role of NO in tumor biology …

Nitric oxide: role in tumour biology and iNOS/NO-based anticancer therapies

S Singh, AK Gupta - Cancer chemotherapy and pharmacology, 2011 - Springer
Purpose The diatomic radical nitric oxide (NO) has been the cause of intense debate with
implication in carcinogenesis, tumour progression, invasion, angiogenesis and modulation …

NO news is not necessarily good news in cancer

S Ekmekcioglu, CH Tang… - Current cancer drug …, 2005 - ingentaconnect.com
The diatomic radical nitric oxide has been the focus of numerous studies involved with every
facet of cancer. It has been implicated in carcinogenesis, progression, invasion, metastasis …

The multifaceted roles of nitric oxide in cancer.

DA Wink, Y Vodovotz, J Laval, F Laval… - …, 1998 - academic.oup.com
The roles of nitric oxide (NO) in numerous disease states have generated considerable
discussion over the past several years. NO has been labeled as the causative agent in …

Nitric oxide, a double edged sword in cancer biology: searching for therapeutic opportunities

S Mocellin, V Bronte, D Nitti - Medicinal research reviews, 2007 - Wiley Online Library
Nitric oxide (NO) is a pleiotropic molecule critical to a number of physiological and
pathological processes. The last decade has witnessed major advances in dissecting NO …

Targeting nitric oxide for cancer therapy

D Hirst, T Robson - Journal of Pharmacy and Pharmacology, 2007 - Wiley Online Library
A blueprint for the ideal anticancer molecule would include most of the properties of nitric
oxide (NO•), but the ability to exploit these characteristics in a therapeutic setting requires a …

Contribution of nitric oxide-mediated apoptosis to cancer metastasis inefficiency

K Xie, S Huang - Free Radical Biology and Medicine, 2003 - Elsevier
Metastasis is largely an unsuccessful process, because the majority of disseminating tumor
cells demise shortly after reaching distant organs. Therefore, survival is essential for …

The regulation of nitric oxide in tumor progression and therapy

Y Hu, J Xiang, L Su, X Tang - Journal of International …, 2020 - journals.sagepub.com
Nitric oxide (NO) is a ubiquitous gas with free radical groups that is soluble in water, and
which is involved in numerous physiological functions including inflammatory and immune …