OBJECTIVE: Folate deficiency in early pregnancy and maternal adiposity, independent of
folate intake, lead to a greater risk of neural tube defects in infants. Atypical antipsychotics …

Objective: Evidence from many different lines of research supports the hypothesis that
schizophrenia is a disorder of development with etiological factors implicated as early as the …

It is hypothesised that the risk of schizophrenia may be elevated in children conceived
following a short interpregnancy interval, when maternal folate stores are still being …

In this review, we examine and compare epidemiological studies of schizophrenia and
neural tube defects (NTDs). Although there is no apparent link between these 2 disparate …

Two apparently unrelated disorders, neural tube defects (NTD) and schizophrenia showed
increased risks in birth cohorts exposed to famine during early gestation. NTD is associated …

Pregnancy burdens maternal folate reserves. Postpartum restoration to normal folate values
may take up to 1 year. Maternal folate deficiency during early pregnancy has been …

Purpose/Background High risks of neural tube defects and other teratogenic effects are
associated with exposure in early pregnancy to some anticonvulsants, including in women …

Background: An increased risk of both schizophrenia and neural tube defects was observed
in a birth cohort exposed to famine during early gestation. Neural tube defects have been …

Converging evidence suggests that a neurodevelopmental disruption plays a role in the
vulnerability to schizophrenia. The authors review evidence supporting in utero exposure to …

Context Elevated prenatal homocysteine level is a plausible risk factor for schizophrenia
because of its partial antagonism ofN-methyl-D-aspartate receptors under physiologic …