Female gut and genital tract microbiota-induced crosstalk and differential effects of short-chain fatty acids on immune sequelae

E Amabebe, DOC Anumba - Frontiers in Immunology, 2020 - frontiersin.org
The gut and genital tract microbiota of females represent very complex biological
ecosystems that are in continuous communication with each other. The crosstalk between …

Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis

M Aldunate, D Srbinovski, AC Hearps… - Frontiers in …, 2015 - frontiersin.org
Lactic acid and short chain fatty acids (SCFAs) produced by vaginal microbiota have
reported antimicrobial and immune modulatory activities indicating their potential as …

Distinct immune responses elicited from cervicovaginal epithelial cells by lactic acid and short chain fatty acids associated with optimal and non-optimal vaginal …

DJ Delgado-Diaz, D Tyssen, JA Hayward… - Frontiers in cellular …, 2020 - frontiersin.org
Non-optimal vaginal microbiota, as observed in bacterial vaginosis (BV), is typically
characterized by a depletion of beneficial lactobacilli and an abundance of numerous …

Short‐chain fatty acids induce pro‐inflammatory cytokine production alone and in combination with toll‐like receptor ligands

P Mirmonsef, MR Zariffard, D Gilbert… - American Journal of …, 2012 - Wiley Online Library
Citation Mirmonsef P, Zariffard MR, Gilbert D, Makinde H, Landay, AL, Spear GT. Short‐
chain fatty acids induce pro‐inflammatory cytokine production alone and in combination with …

Gut microbiota and immune system interactions

JY Yoo, M Groer, SVO Dutra, A Sarkar, DI McSkimming - Microorganisms, 2020 - mdpi.com
Dynamic interactions between gut microbiota and a host's innate and adaptive immune
systems are essential in maintaining intestinal homeostasis and inhibiting inflammation. Gut …

[HTML][HTML] Immunomodulatory roles of microbiota-derived short-chain fatty acids in bacterial infections

R Ranjbar, SN Vahdati, S Tavakoli, R Khodaie… - Biomedicine & …, 2021 - Elsevier
In recent years, an overwhelming amount of evidence has positively recommended a
significant role of microbiota in human health and disease. Microbiota also plays a crucial …

Physiological changes and interactions between microbiome and the host during pregnancy

ZZ Zakaria, S Al-Rumaihi, RS Al-Absi… - Frontiers in Cellular …, 2022 - frontiersin.org
In recent years, it has become clear that microbiome play a variety of essential roles in
human metabolism, immunity, and overall health and that the composition of these …

The female reproductive tract microbiotas, inflammation, and gynecological conditions

M Gholiof, E Adamson-De Luca… - Frontiers in Reproductive …, 2022 - frontiersin.org
The intricate interactions between the host cells, bacteria, and immune components that
reside in the female reproductive tract (FRT) are essential in maintaining reproductive tract …

Lactic acid enhances vaginal epithelial barrier integrity and ameliorates inflammatory effects of dysbiotic short chain fatty acids and HIV-1

I Schwecht, A Nazli, B Gill, C Kaushic - Scientific Reports, 2023 - nature.com
The vaginal microenvironment is key in mediating susceptibility to sexually transmitted
infections. A polymicrobial environment with reduced Lactobacilllus spp. is characteristic of …

The emerging role of microbiota-derived short-chain fatty acids in immunometabolism

SA Jasim, MJC Opulencia, AA Ramírez-Coronel… - International …, 2022 - Elsevier
The accumulating evidence revealed that microbiota plays a significant function in training,
function, and the induction of host immunity. Once this interaction (immune system …