The human genome encodes the blueprint of life, but the function of the vast majority of its
nearly three billion bases is unknown. The Encyclopedia of DNA Elements (ENCODE) …

We report the generation and analysis of functional data from multiple, diverse experiments
performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE …

The reference human genome sequence set the stage for studies of genetic variation and its
association with human disease, but epigenomic studies lack a similar reference. To …

The laboratory mouse shares the majority of its protein-coding genes with humans, making it
the premier model organism in biomedical research, yet the two mammals differ in …

The human and mouse genomes contain instructions that specify RNAs and proteins and
govern the timing, magnitude, and cellular context of their production. To better delineate …

There has been much progress in genomics in the ten years since a draft sequence of the
human genome was published. Opportunities for understanding health and disease are now …

The Encyclopedia of DNA Elements (ENCODE) project dishes up a hearty banquet of data
that illuminate the roles of the functional elements of the human genome. Here, six scientists …

The human and mouse genomes contain instructions that specify RNAs and proteins and
govern the timing, magnitude, and cellular context of their production. To better delineate …

Abstract The Encylopedia of DNA Elements (ENCODE) Project launched in 2003 with the
long-term goal of developing a comprehensive map of functional elements in the human …

The sequence of the human genome has dramatically accelerated biomedical research.
Here I explore its impact, in the decade since its publication, on our understanding of the …