The obese gene product, leptin is an important circulating satiety factor that regulates energy
balance via its actions in the hypothalamus. However, leptin receptors are also expressed in …

It is well documented that leptin is a circulating hormone that plays a key role in regulating
food intake and body weight via its actions on specific hypothalamic nuclei. However, leptin …

Leptin is an important circulating factor that regulates energy balance via the leptin receptor
Ob-Rb in the hypothalamus. Ob-Rb activation may inhibit hypothalamic neurons by …

ABSTRACT Phosphoinositide 3‐kinase (PI3‐kinase) has been shown to link leptin receptor
activation to stimulation of large conductance Ca2+‐activated K+ (BK) channels and …

The obese gene product leptin is an important signaling protein that regulates food intake
and body weight via activation of the hypothalamic leptin receptor (Ob-Rb; Jacob et al …

Leptin, a hormone produced by adipocytes, provides signals to specific regions of the
hypothalamus to control energy homeostasis. However, the past decade of research has not …

Hippocampal plasticity is triggered by a variety of stimuli including sensory inputs,
neurotrophins and inflammation. Leptin, whose primary function is to regulate food intake …

It is well documented that the hormone leptin regulates energy balance via its actions in the
hypothalamus. However, evidence is accumulating that leptin plays a key role in numerous …

Leptin, an adipocytokine encoded by an obesity gene and expressed in adipose tissue,
affects feeding behavior, thermogenesis, and neuroendocrine status via leptin receptors …

Besides regulating energy balance and reducing body-weight, the adipokine leptin has
been recently shown to be neuroprotective and antiapoptotic by promoting neuronal survival …