Cordycepin alleviates airway hyperreactivity in a murine model of asthma by attenuating the inflammatory process

X Yang, Y Li, Y He, T Li, W Wang, J Zhang, J Wei… - International …, 2015 - Elsevier
Cordycepin (Cor), which is a naturally occurring nucleoside derivative isolated from
Cordyceps militaris, has been shown to exert excellent antiinflammatory activity in a murine …

Cordycepin inhibits LPS-induced acute lung injury by inhibiting inflammation and oxidative stress

J Lei, Y Wei, P Song, Y Li, T Zhang, Q Feng… - European Journal of …, 2018 - Elsevier
Acute lung injury (ALI) is a common severe clinical syndrome in intensive care unit.
Inflammation has been reported to play a critical role in the development of ALI. Cordycepin …

Cordycepin inhibits airway remodeling in a rat model of chronic asthma

X Fei, X Zhang, G Zhang, W Bao, Y Zhang… - Biomedicine & …, 2017 - Elsevier
The potential suppression role of cordycepin (Cor) on airway remodeling in a rat model of
chronic asthma was investigated in this paper. We evaluated the anti-remodeling of Cor (50 …

The Extract of Cordyceps sinensis Inhibited Airway Inflammation by Blocking NF-κB Activity

YL Chiou, CY Lin - Inflammation, 2012 - Springer
Aiming the extract of Cordyceps sinensis significantly inhibits airway inflammation, airway
hyperresponsiveness, and the infiltration of eosinophils in the airway of rats and may be …

The effects of cordycepin on ovalbumin-induced allergic inflammation by strengthening Treg response and suppressing Th17 responses in ovalbumin-sensitized mice

Z Tianzhu, Y Shihai, D Juan - Inflammation, 2015 - Springer
The aim of the current study was to use a mouse model of allergic asthma to investigate
whether cordycepin has antiasthmatic effects, and if so, to determine the mechanism of …

Cordycepin alleviates lipopolysaccharide-induced acute lung injury via Nrf2/HO-1 pathway

R Qing, Z Huang, Y Tang, Q Xiang, F Yang - International …, 2018 - Elsevier
Aims The present study is to investigate the protective effect of cordycepin on inflammatory
reactions in rats with acute lung injury (ALI) induced by lipopolysaccharide (LPS), as well as …

Anti-inflammatory effects of cordycepin in lipopolysaccharide-stimulated RAW 264.7 macrophages through Toll-like receptor 4-mediated suppression of mitogen …

YH Choi, GY Kim, HH Lee - Drug Design, Development and …, 2014 - Taylor & Francis
Cordycepin is the main functional component of the Cordyceps species, which has been
widely used in traditional Oriental medicine. This compound possesses many …

Cordycepin inhibits lipopolysaccharide-induced inflammation by the suppression of NF-κB through Akt and p38 inhibition in RAW 264.7 macrophage cells

HG Kim, B Shrestha, SY Lim, DH Yoon… - European journal of …, 2006 - Elsevier
Cordyceps militaris, a caterpillar-grown traditional medicinal mushroom, produces an
important bioactive compound, cordycepin (3′-deoxyadenosine). Cordycepin is reported to …

Cordycepin attenuates IFN-γ-induced macrophage IP-10 and mig expressions by inhibiting STAT1 activity in CFA-induced inflammation mice model

R Yang, X Wang, D Xi, J Mo, K Wang, S Luo, J Wei… - Inflammation, 2020 - Springer
Cordycepin, a natural derivative of adenosine, has been shown to exert pharmacological
properties including anti-oxidation, antitumor, and immune regulation. It is reported that …

Cordyceps polysaccharide ameliorates airway inflammation in an ovalbumin-induced mouse model of asthma via TGF-β1/Smad signaling pathway

Y Zheng, L Li, T Cai - Respiratory Physiology & Neurobiology, 2020 - Elsevier
Allergic asthma is a chronic inflammatory disease characterized by airflow obstruction,
airway hyperresponsiveness (AHR), airway inflammation, and mucus overproduction …