Background Randomized trials have shown that low-dose aspirin decreases the risk of a first
myocardial infarction in men, with little effect on the risk of ischemic stroke. There are few …

ContextAspirin therapy reduces the risk of cardiovascular disease in adults who are at
increased risk. However, it is unclear if women derive the same benefit as men. ObjectiveTo …

Objective.—The aim of the study was to examine prospectively the association between
regular aspirin use and the risk of a first myocardial infarction and other cardiovascular …

Background In 1988, the aspirin component of the Physicians' Health Study, a randomized,
double-blind, placebo-controlled trial of 22 071 apparently healthy men was terminated …

Background: Cardiovascular disease (CVD) is the leading cause of death in the United
States. Purpose: To update a systematic review about the benefits of aspirin for the primary …

Despite hundreds of clinical trials, the appropriate dose of aspirin to prevent myocardial
infarction (MI) and stroke is uncertain. In the US, the doses most frequently recommended …

Until recently, 5 major studies have formed the basis for the use of aspirin (acetylsalicylic
acid) in primary prevention of cardiovascular (CV) events. Despite these data, the role of …

Background The cost-effectiveness of aspirin for primary prevention of cardiovascular events
in women is unclear. We sought to perform a cost-utility analysis to address this issue …

Objective To evaluate the benefits and harms of aspirin for the primary prevention of CVD
and determine whether the effects vary by sex and diabetes status. Methods We searched …

Background—Aspirin is effective for the primary prevention of cardiovascular events, but it
remains unclear for which subgroups of individuals aspirin is beneficial. We assessed the …