[HTML][HTML] Role of lncRNAs in cellular aging

U Degirmenci, S Lei - Frontiers in endocrinology, 2016 - frontiersin.org
Aging is a universal, intrinsic, and time-dependent biological decay that is linked to intricate
cellular processes including cellular senescence, telomere shortening, stem cell exhaustion …

[HTML][HTML] LncRNAs regulatory networks in cellular senescence

PK Puvvula - International journal of molecular sciences, 2019 - mdpi.com
Long noncoding RNAs (lncRNAs) are a class of transcripts longer than 200 nucleotides with
no open reading frame. They play a key role in the regulation of cellular processes such as …

Role of lncRNAs in aging and age‐related diseases

J He, C Tu, Y Liu - Aging Medicine, 2018 - Wiley Online Library
Aging is progressive physiological degeneration and consequently declined function, which
is linked to senescence on both cellular and organ levels. Accumulating studies indicate that …

Emerging roles of lnc RNA s in senescence

M Montes, AH Lund - The FEBS journal, 2016 - Wiley Online Library
Cellular senescence is a complex stress response that leads to an irreversible state of cell
growth arrest. Senescence may be induced by various stimuli such as telomere shortening …

[HTML][HTML] Long noncoding RNAs (lncRNAs) and the molecular hallmarks of aging

I Grammatikakis, AC Panda, K Abdelmohsen… - Aging (Albany …, 2014 - ncbi.nlm.nih.gov
During aging, progressive deleterious changes increase the risk of disease and death.
Prominent molecular hallmarks of aging are genomic instability, telomere attrition …

[HTML][HTML] Roles of long noncoding RNAs in aging and aging complications

L Jin, Q Song, W Zhang, B Geng, J Cai - Biochimica et Biophysica Acta …, 2019 - Elsevier
Aging is a universal and time dependent complex biological process, characterized by a
progressive physiological dysfunction and an increased vulnerability to death. Though the …

Noncoding RNA control of cellular senescence

K Abdelmohsen, M Gorospe - Wiley Interdisciplinary Reviews …, 2015 - Wiley Online Library
Senescent cells accumulate in normal tissues with advancing age and arise by long‐term
culture of primary cells. Senescence develops following exposure to a range of stress …

Long noncoding RNAs in diseases of aging

J Kim, KM Kim, JH Noh, JH Yoon… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Aging is a process during which progressive deteriorating of cells, tissues, and organs over
time lead to loss of function, disease, and death. Towards the goal of extending human …

LncRNAs regulating stemness in aging

A Sousa‐Franco, K Rebelo, ST da Rocha… - Aging …, 2019 - Wiley Online Library
One of the most outstanding observations from next‐generation sequencing approaches
was that only 1.5% of our genes code for proteins. The biggest part is transcribed but give …

[HTML][HTML] Identification of the lncRNA, AK156230, as a novel regulator of cellular senescence in mouse embryonic fibroblasts

Y Chen, M Cai, S Xu, M Meng, X Ren, JW Yang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs) have gained extensive attentions in recent years because
of their potential importance in a variety of biological and pathological processes. In this …