ATP-dependent nucleosome remodeling and core histone acetylation and deacetylation
represent mechanisms to alter nucleosome structure. NuRD is a multisubunit complex …

The nucleosome remodeling and deacetylase (NuRD) complex regulates chromatin
organization, gene transcription, genomic stability and developmental signaling. NuRD has …

Chromatin remodeling enzymes act to dynamically regulate gene accessibility. In many
cases, these enzymes function as large multicomponent complexes that in general comprise …

ATP-dependent nucleosome remodeling and core histone tail modifications play important
roles in chromatin function. Purification and characterization of the NuRD/Mi-2 complex …

The nucleosome remodeling and deacetylase (NuRD) complex is a widely conserved
transcriptional co-regulator that harbors both nucleosome remodeling and histone …

The DNA in eukaryotic cells is packaged into chromatin, which functions as a boundary to
the transcriptional activation process. The nucleosome is the basic repeating unit of …

Class I histone deacetylase complexes play essential roles in many nuclear processes.
Whilst they contain a common catalytic subunit, they have diverse modes of action …

Transcription regulation through chromatin compaction and decompaction is regulated
through various chromatin-remodeling complexes such as nucleosome remodeling and …

The nucleosome remodeling and deacetylase (NuRD) complex is essential for metazoan
development but has been refractory to biochemical analysis. We present an integrated …

The NuRD complex is a multi-protein transcriptional corepressor that couples histone
deacetylase and ATP-dependent chromatin remodelling activities. The complex regulates …