We report herein an unprecedented atroposelective dynamic kinetic resolution of
Bringmann's lactones with C-nucleophiles. By the use of activated isocyanides as the …

We present here a highly efficient NHC‐catalyzed kinetic resolution of a wide range of 1, 1′‐
biaryl‐2, 2′‐diols and amino alcohols to provide them in uniformly≥ 99% ee. This …

Axially chiral amino acids and its derivatives are vital building blocks of bioactive molecules,
artificial peptides, and asymmetric catalysts. Herein, we report an unprecedented carbene …

Herein we present a highly efficient N-heterocyclic-carbene (NHC)-catalyzed
atroposelective acylation of amino bisphenols to provide access to a wide range of 1, 1 …

N-Heterocyclic carbene (NHC)-catalyzed enantioselective aldol lactonization of acyclic
ketoacids, proceeding via dynamic kinetic resolution, is presented. The carbene generated …

A CuH-catalyzed atropoenantioselective reduction of Bringmann's lactones via dynamic
kinetic resolution has been disclosed. This protocol features a broad substrate scope and …

A solution to the unmet synthetic challenge of achieving highly atropo-enantioselective
transesterification of Bringmann's lactones has been realized, employing a chiral …

Organocatalytic dynamic kinetic resolution of configurationally labile cyclic molecules
represents one of the most efficient methods for the atroposelective construction of axially …

The atom‐and step‐efficient synthesis of chiral fused tricyclic lactams from readily available
ketoesters using cheap ammonium salts as the nitrogen source is reported. This ruthenium …

Axially chiral phenols are attractive targets in organic synthesis. This motif is central to many
natural products and widely used as precursors to, or directly, as chiral ligands and …