In eukaryotic nuclei, DNA is wrapped around an octamer of core histones to form
nucleosomes, and chromatin fibers are thought to be stabilized by linker histones of the H1 …

Linker histone H1 is located on the surface of the nucleosome where it interacts with the
linker DNA region and stabilizes the 30-nm chromatin fiber. Vertebrates have several …

Eukaryotic nucleosomes organize chromatin by wrapping 147 bp of DNA around a histone
core particle comprising two molecules each of histone H2A, H2B, H3 and H4. The DNA …

Most eukaryotic cells contain nearly equimolar amounts of nucleosomes and H1 linker
histones. Despite their abundance and the potential functional specialization of H1 subtypes …

The importance of histone H1 heterogeneity and total H1 stoichiometry in chromatin has
been enigmatic. Here we report a detailed characterization of the chromatin structure of cells …

At least six histone H1 variants exist in somatic mammalian cells that bind to the linker DNA
and stabilize the nucleosome particle contributing to higher order chromatin compaction. In …

The eukaryotic genome is packed into chromatin, a nucleoprotein complex mainly formed by
the interaction of DNA with the abundant basic histone proteins. The fundamental structural …

Histones H3 and H4 have a well defined structural role in the nucleosome and an
established role in the regulation of transcription. We have made use of a microinjection …

Linker histones of which histone H1 is a representative are a diverse family of architectural
proteins within the eukaryotic nucleus. These proteins have a variety of structures, but …

Abstract Since Robert Feulgen first stained DNA in the cell, visualizing genome chromatin
has been a central issue in cell biology to uncover how chromatin is organized and behaves …