The positioning of nucleosomes along chromatin has been implicated in the regulation of
gene expression in eukaryotic cells, because packaging DNA into nucleosomes affects …

Near the 5′ end of most eukaryotic genes, nucleosomes form highly regular arrays that
begin at canonical distances from the transcriptional start site. Determinants of this and other …

The positioning of nucleosomes within the coding regions of eukaryotic genes is aligned
with respect to transcriptional start sites. This organization is likely to influence many genetic …

Nucleosomes are the basic packaging units of chromatin, modulating accessibility of
regulatory proteins to DNA and thus influencing eukaryotic gene regulation. Elaborate …

The exact positions of nucleosomes along genomic DNA can influence many aspects of
chromosome function. However, existing methods for mapping nucleosomes do not provide …

We present the first complete high-resolution map of nucleosome occupancy across the
whole Saccharomyces cerevisiae genome, identifying over 70,000 positioned nucleosomes …

DNA sequence has long been recognized as an important contributor to nucleosome
positioning, which has the potential to regulate access to genes. The extent to which the …

Nucleosome organization is critical for gene regulation. In living cells this organization is
determined by multiple factors, including the action of chromatin remodellers, competition …

Eukaryotic genomes are packaged into nucleosome particles that occlude the DNA from
interacting with most DNA binding proteins. Nucleosomes have higher affinity for particular …

Nucleosome positioning is critical to chromatin accessibility and is associated with gene
expression programs in cells,–. Previous nucleosome mapping methods assemble profiles …