Gene expression signature in patients with symptomatic peripheral artery disease

JD Newman, MIG Cornwell, H Zhou… - … , and vascular biology, 2021 - Am Heart Assoc
Objective: Peripheral artery disease (PAD) is an atherothrombotic disease of the lower limbs
with substantial morbidity and mortality. We used next-generation sequencing to identify …

Peripheral arterial occlusive disease: global gene expression analyses suggest a major role for immune and inflammatory responses

S Fu, H Zhao, J Shi, A Abzhanov, K Crawford… - Bmc Genomics, 2008 - Springer
Background Peripheral arterial disease (PAD), a major manifestation of atherosclerosis, is
associated with significant cardiovascular morbidity, limb loss and death. However …

Biomarkers of peripheral arterial disease

JP Cooke, AM Wilson - Journal of the American College of Cardiology, 2010 - jacc.org
Atherosclerotic arterial occlusive disease affecting the lower extremities is also known as
peripheral artery disease (PAD). This disorder affects 8 to 12 million individuals in the US …

Molecular characterization of peripheral arterial disease in proximal extremity arteries

RS Croner, K Balzer, V Schellerer, V Müller… - journal of surgical …, 2012 - Elsevier
PURPOSE: Although risk factors for atherosclerosis in peripheral arterial disease (PAD) are
well defined, the underlying mechanisms are poorly understood and no medication exists for …

Genome-wide association study of peripheral artery disease

NR Van Zuydam, A Stiby, M Abdalla… - Circulation: Genomic …, 2021 - Am Heart Assoc
Background: Peripheral artery disease (PAD) affects> 200 million people worldwide and is
associated with high mortality and morbidity. We sought to identify genomic variants …

Biomarkers and genetics in peripheral artery disease

S Hazarika, BH Annex - Clinical chemistry, 2017 - academic.oup.com
BACKGROUND Peripheral artery disease (PAD) is highly prevalent and there is
considerable diversity in the initial clinical manifestation and disease progression among …

Gene expression profiling of peripheral blood mononuclear cells in the setting of peripheral arterial disease

R Masud, K Shameer, A Dhar, K Ding… - Journal of clinical …, 2012 - Springer
Background Peripheral arterial disease (PAD) is a relatively common manifestation of
systemic atherosclerosis that leads to progressive narrowing of the lumen of leg arteries …

Assessment of gene expression profiles in peripheral occlusive arterial disease

S Bubenek, A Nastase, AM Niculescu, S Baila… - Canadian Journal of …, 2012 - Elsevier
Background Molecular events responsible for the onset and progression of peripheral
occlusive arterial disease (POAD) are incompletely understood. Gene expression profiling …

Differential microRNA expression profiles in peripheral arterial disease

PW Stather, N Sylvius, JB Wild, E Choke… - Circulation …, 2013 - Am Heart Assoc
Background—Peripheral arterial disease (PAD) is a clinical condition caused by an
atherosclerotic process affecting the arteries of the limbs. Despite major improvements in …

[HTML][HTML] Epigenetic Regulation of Angiogenesis in Peripheral Artery Disease

NK Malhi, KW Southerland, L Lai… - Methodist DeBakey …, 2023 - ncbi.nlm.nih.gov
Peripheral arterial disease (PAD) represents a global health concern with a rising
prevalence attributed to factors such as obesity, diabetes, aging, and smoking. Among …