[HTML][HTML] Fluorescence lifetime imaging of endogenous biomarker of oxidative stress

R Datta, A Alfonso-García, R Cinco, E Gratton - Scientific reports, 2015 - nature.com
Presence of reactive oxygen species (ROS) in excess of normal physiological level results in
oxidative stress. This can lead to a range of pathological conditions including inflammation …

[HTML][HTML] Non-invasive real-time imaging of reactive oxygen species (ROS) using auto-fluorescence multispectral imaging technique: A novel tool for redox biology

A Habibalahi, MD Moghari, JM Campbell, AG Anwer… - Redox biology, 2020 - Elsevier
Detecting reactive oxygen species (ROS) that play a critical role as redox modulators and
signalling molecules in biological systems currently requires invasive methods such as ROS …

Fluorescence imaging for visualizing the bioactive molecules of lipid peroxidation within biological systems

D Su, X Wang, W Zhang, P Li, B Tang - TrAC Trends in Analytical …, 2022 - Elsevier
Lipid peroxidation is accompanied with producing series of bioactive molecules, including
lipid radicals, lipid peroxyl radicals, lipid hydroperoxide and some reactive carbonyl species …

Recent progress of oxidative stress associated biomarker detection

J Li, L Pan, W Pan, N Li, B Tang - Chemical Communications, 2023 - pubs.rsc.org
Oxidative stress denotes the imbalance between the generation of reactive oxygen species
(ROS) and antioxidant defenses in living organisms, participating in various …

[HTML][HTML] Recent progress in the development of fluorescent probes for imaging pathological oxidative stress

Y Geng, Z Wang, J Zhou, M Zhu, J Liu… - Chemical Society …, 2023 - pubs.rsc.org
Oxidative stress is closely related to the physiopathology of numerous diseases. Reactive
oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS) …

A FRET-based ratiometric redox probe for detecting oxidative stress by confocal microscopy, FLIM and flow cytometry

A Kaur, MA Haghighatbin, CF Hogan… - Chemical …, 2015 - pubs.rsc.org
Understanding the role of oxidative stress in disease requires real time monitoring of redox
status within a cell. We report a FRET-based, ratiometric redox probe which can be applied …

Visualizing oxidative cellular stress induced by nanoparticles in the subcytotoxic range using fluorescence lifetime imaging

J Balke, P Volz, F Neumann, R Brodwolf, A Wolf… - Small, 2018 - Wiley Online Library
Nanoparticles hold a great promise in biomedical science. However, due to their unique
physical and chemical properties they can lead to overproduction of intracellular reactive …

Aurone derivative revealing the metabolism of lipid droplets and monitoring oxidative stress in living cells

K Wang, S Ma, Y Ma, Y Zhao, M Xing, L Zhou… - Analytical …, 2020 - ACS Publications
Lipid droplets (LDs) are closely connected to many physiological processes and abnormal
LDs are related to many diseases. Herein, a family of two-photon fluorescence compounds …

Fluorescence probes to detect lipid-derived radicals

K Yamada, F Mito, Y Matsuoka, S Ide… - Nature chemical …, 2016 - nature.com
Lipids and their metabolites are easily oxidized in chain reactions initiated by lipid radicals,
forming lipid peroxidation products that include the electrophiles 4-hydroxynonenal and …

Rate of lipid peroxyl radical production during cellular homeostasis unraveled via fluorescence imaging

LE Greene, R Lincoln, G Cosa - Journal of the American Chemical …, 2017 - ACS Publications
Reactive oxygen species (ROS) and their associated byproducts have been traditionally
associated with a range of pathologies. It is now believed, however, that at basal levels …