1 Blind patch clamp recordings were made from substantia gelatinosa (SG) neurones in the
adult rat spinal cord slice to study the mechanisms of cholinergic modulation of GABAergic …

1. gamma-Aminobutyric acid (GABA) is thought to inhibit both pre-and postsynaptically the
transfer of nociceptive signals from primary afferent fibers to spinal dorsal horn sensory cells …

We have previously provided functional evidence that glycine and GABA are contained in
the same synaptic vesicles and coreleased at the same synapses in lamina I of the rat spinal …

Spinally administered muscarinic receptor agonists or acetylcholinesterase inhibitors
produce efficacious analgesia. However, the mechanisms of the antinociceptive actions of …

GABAA receptor‐mediated presynaptic depolarization is believed to induce presynaptic
inhibition of excitatory synaptic transmission. We report here the functional roles of …

These experiments examined the effects of intrathecally administered gamma-aminobutyric
acid (GABA) agonists on the effects of intrathecally administered excitatory amino acid (EAA) …

Spinally administered muscarinic receptor agonists or acetylcholinesterase inhibitors can
produce antinociception. However, the mechanisms of the action of cholinergic agents in the …

1 Many inhibitory nerve terminals in the mammalian anteroventral cochlear nucleus (AVCN)
contain both glycine and GABA, but the reason for the co‐localization of these two inhibitory …

We used whole-cell recording to identify, for the first time, GABAergic tonic current in
subpopulations of substantia gelatinosa neurons in mouse spinal cord slices. Application of …

Colocalization of GABA and glycine in synaptic terminals of the superficial dorsal horn raises
the question of their relative contribution to inhibition of different classes of neurons in this …