Inherited thrombophilia in the era of direct oral anticoagulants

L Khider, N Gendron, L Mauge - International Journal of Molecular …, 2022 - mdpi.com
Severe inherited thrombophilia includes rare deficiencies of natural anticoagulants
(antithrombin and proteins C and S) and homozygous or combined factor V Leiden and FII …

The use of direct oral anticoagulants in inherited thrombophilia

JW Skelley, CW White, AR Thomason - Journal of thrombosis and …, 2017 - Springer
To review the use of the direct oral anticoagulant (DOAC) agents in inherited thrombophilia
based on the literature. MEDLINE, International Pharmaceutical Abstracts, and Google …

Thrombophilia: 2009 update

P Foy, S Moll - Current treatment options in cardiovascular medicine, 2009 - Springer
As venous thrombosis is mostly caused by disturbances in the plasma coagulation system,
abnormalities of coagulation factors are mostly risk factors for venous thromboembolism …

Direct oral anticoagulants in patients with inherited thrombophilia and venous thromboembolism: a prospective cohort study

E Campello, L Spiezia, C Simion… - Journal of the …, 2020 - Am Heart Assoc
Background In this prospective cohort study, we aimed to evaluate the efficacy and safety of
direct oral anticoagulants (DOACs) versus heparin/vitamin K antagonists for the treatment of …

Current practise of testing for inherited thrombophilia

M Coppens, JA van Mourik, CM Eckmann… - Journal of Thrombosis …, 2007 - jthjournal.org
About half of all episodes of venous thromboembolism (VTE, ie deep vein thrombosis and
pulmonary embolism) are elicited by an acquired clinical risk factor, such as recent surgery …

[HTML][HTML] Direct oral anticoagulants in patients affected by major congenital thrombophilia

A Serrao, B Lucani, D Mansour, A Ferretti… - … of Hematology and …, 2019 - ncbi.nlm.nih.gov
Background Thrombophilia is a condition that predisposes to a higher incidence of venous
thromboembolisms (VTE), some also in atypical sites. Direct oral anticoagulants (DOACs) …

Non-vitamin K antagonist oral anticoagulants in patients with severe inherited thrombophilia: a series of 33 patients

A Undas, T Goralczyk - Blood Coagulation & Fibrinolysis, 2017 - journals.lww.com
The aim of the study was to investigate whether treatment with non-vitamin K antagonist oral
anticoagulants (NOACs) is effective and well tolerated in real-life patients following venous …

[HTML][HTML] Thrombophilia testing in the era of direct oral anticoagulants

J Darlow, H Mould - Clinical Medicine, 2021 - Elsevier
Venous thromboembolism (VTE) is increasingly recognised in primary and secondary care
practice. The arrival of direct oral anticoagulants (DOACs) has made the management of …

Oral anticoagulant therapy—When art meets science

PL Cîmpan, RI Chira, M Mocan, FP Anton… - Journal of Clinical …, 2019 - mdpi.com
Anticoagulant treatment is extremely important and frequently encountered in the therapy of
various cardiovascular diseases. Vitamin K antagonists (VKA) are in use for the prevention …

Classic thrombophilic gene variants

PM Mannucci, M Franchini - Thrombosis and haemostasis, 2015 - thieme-connect.com
Thrombophilia is defined as a condition predisposing to the development of venous
thromboembolism (VTE) on the basis of a hypercoagu-lable state. Over the past decades …