Two new P2X receptor cDNAs (P2X5 and P2X6) were isolated and expressed. All six
proteins are 36–48 percent identical and seem to have two transmembrane segments with a …

We have isolated the cDNA for a novel member (P2X6) of the ATP-gated ion channel family.
The rat P2X6nucleotide sequence encodes a 379 amino acid protein that conserves all the …

ATP-gated ion channels (P2X receptors) are abundantly expressed in both neuronal and
nonneuronal tissues, where they can serve as postsynaptic receptors. The response to ATP …

The mammalian P2X receptor gene family encodes two-transmembrane domain
nonselective cation channels gated by extracellular ATP. Anatomical localization data …

P2X receptors are membrane ion channels that open in response to the binding of
extracellular ATP. Seven genes in vertebrates encode P2X receptor subunits, which are 40 …

A cDNA was cloned which encodes a new ATP‐gated ion channel (P2X4 receptor). ATP
induces a cationic current in HEK293 cells transfected with the P2X4 receptor. However, the …

P2X receptors are ion channels gated by extracellular ATP. We report here cloning of a
P2X2 receptor splice variant (P2X2-2) carrying a 207 bp deletion in the intracellular C …

The distribution of the P2X2 receptor subunit of the adenosine 5′‐triphosphate (ATP)‐
gated ion channels was examined in the adult rat central nervous system (CNS) by using …

The distribution of P2X1, P2X2, P2X3, P2X4, P2X5 and P2X6 receptors, a family of ATP-
gated cation channels, in rat trigeminal, dorsal root, nodose, superior cervical, and coeliac …

P2X2 and P2X3 are subunits of P2X receptors, cation channels opened by binding
extracellular ATP. cDNAs encoding P2X2 and P2X3 receptor subunits, each with one of two …