Malaria Parasite Infection Compromises Control of Concurrent Systemic Non-typhoidal Salmonella Infection via IL-10-Mediated Alteration of Myeloid Cell Function
Non-typhoidal Salmonella serotypes (NTS) cause a self-limited gastroenteritis in
immunocompetent individuals, while children with severe Plasmodium falciparum malaria …
immunocompetent individuals, while children with severe Plasmodium falciparum malaria …
Inflammation-associated alterations to the intestinal microbiota reduce colonization resistance against non-typhoidal Salmonella during concurrent malaria parasite …
Childhood malaria is a risk factor for disseminated infections with non-typhoidal Salmonella
(NTS) in sub-Saharan Africa. While hemolytic anemia and an altered cytokine environment …
(NTS) in sub-Saharan Africa. While hemolytic anemia and an altered cytokine environment …
Malaria parasite-mediated alteration of macrophage function and increased iron availability predispose to disseminated nontyphoidal Salmonella infection
Disseminated infections with nontyphoidal Salmonella (NTS) are a significant cause of child
mortality in sub-Saharan Africa. NTS infection in children is clinically associated with …
mortality in sub-Saharan Africa. NTS infection in children is clinically associated with …
[HTML][HTML] The mucosal inflammatory response to non-typhoidal Salmonella in the intestine is blunted by IL-10 during concurrent malaria parasite infection
Coinfection can markedly alter the response to a pathogen, thereby changing its clinical
presentation. For example, non-typhoidal Salmonella (NTS) serotypes are associated with …
presentation. For example, non-typhoidal Salmonella (NTS) serotypes are associated with …
Parasite-Specific CD4+ IFN-γ+ IL-10+ T Cells Distribute within Both Lymphoid and Nonlymphoid Compartments and Are Controlled Systemically by Interleukin-27 …
A Villegas-Mendez, TN Shaw, CA Inkson… - Infection and …, 2016 - Am Soc Microbiol
Immune-mediated pathology in interleukin-10 (IL-10)-deficient mice during blood-stage
malaria infection typically manifests in nonlymphoid organs, such as the liver and lung …
malaria infection typically manifests in nonlymphoid organs, such as the liver and lung …
Malaria, anemia, and invasive bacterial disease: A neutrophil problem?
JP Mooney, LJ Galloway… - Journal of Leukocyte …, 2019 - academic.oup.com
Invasive bacterial disease is well described in immunocompromised hosts, including those
with malaria infection. One bacterial infection frequently observed in children with …
with malaria infection. One bacterial infection frequently observed in children with …
Both Hemolytic Anemia and Malaria Parasite-Specific Factors Increase Susceptibility to Nontyphoidal Salmonella enterica Serovar Typhimurium Infection in Mice
Severe pediatric malaria is an important risk factor for developing disseminated infections
with nontyphoidal Salmonella serotypes (NTS). While recent animal studies on this subject …
with nontyphoidal Salmonella serotypes (NTS). While recent animal studies on this subject …
IL‐23 protection against Plasmodium berghei infection in mice is partially dependent on IL‐17 from macrophages
Although IL‐12 is believed to contribute to protective immune responses, the role played by
IL‐23 (a member of the IL‐12 family) in malaria is elusive. Here, we show that IL‐23 is …
IL‐23 (a member of the IL‐12 family) in malaria is elusive. Here, we show that IL‐23 is …
Role of Interleukin‐10 in Malaria: Focusing on Coinfection with Lethal and Nonlethal Murine Malaria Parasites
M Niikura, SI Inoue, F Kobayashi - BioMed Research …, 2011 - Wiley Online Library
Interleukin‐(IL‐) 10, anti‐inflammatory cytokine, is known to inhibit the protective immune
responses against malaria parasites and to be involved in exacerbating parasitemia during …
responses against malaria parasites and to be involved in exacerbating parasitemia during …
Impaired Macrophage Responses May Contribute to Exacerbation of Blood-Stage Plasmodium chabaudi chabaudi Malaria in Interleukin-12-Deficient Mice
Aiming to clarify the role of endogenous interleukin-12 (IL-12) in protective immunity against
blood stages of Plasmodium chabaudi chabaudi (AS), we evaluated the course of infection …
blood stages of Plasmodium chabaudi chabaudi (AS), we evaluated the course of infection …