Relation of concavity in the expiratory flow-volume loop to dynamic hyperinflation during exercise in COPD

J Varga, R Casaburi, S Ma, A Hecht, D Hsia… - Respiratory physiology …, 2016 - Elsevier
Active expiration during exercise can increase intrathoracic pressure yielding concavity in
the expiratory flow-volume loop in COPD. We investigated the relationship between this …

[HTML][HTML] Breath-by-breath quantification of progressive airflow limitation during exercise in COPD: a new method

S Ma, A Hecht, J Varga, M Rambod, S Morford… - Respiratory …, 2010 - Elsevier
During heavy exercise in chronic obstructive pulmonary disease (COPD), dynamic airways
compression leads to a progressive fall in intrabreath flow. This is manifested by concavity in …

The major limitation to exercise performance in COPD is dynamic hyperinflation

DE O'Donnell, KA Webb - Journal of applied physiology, 2008 - journals.physiology.org
The inability to engage in sustained physical activity is a common feature of chronic
obstructive pulmonary disease (COPD) and contributes importantly to the perception of poor …

Repeatability of inspiratory capacity during incremental exercise in patients with severe COPD

TE Dolmage, RS Goldstein - Chest, 2002 - Elsevier
Study objective Estimating lung volume using inspiratory capacity (IC) maneuvers is a useful
way of tracking dynamic hyperinflation. An understanding of the repeatability of the IC in a …

Does expiratory muscle activity influence dynamic hyperinflation and exertional dyspnea in COPD?

P Laveneziana, KA Webb, K Wadell, JA Neder… - Respiratory physiology …, 2014 - Elsevier
Increased expiratory muscle activity is common during exercise in patients with COPD but its
role in modulating operating lung volumes and dyspnea during incremental cycle ergometry …

Regional chest wall volumes during exercise in chronic obstructive pulmonary disease

A Aliverti, N Stevenson, RL Dellaca, AL Mauro… - Thorax, 2004 - thorax.bmj.com
Background: Dynamic hyperinflation of the lungs impairs exercise performance in chronic
obstructive pulmonary disease (COPD). However, it is unclear which patients are affected by …

Determinants of dynamic hyperinflation during metronome-paced tachypnea in COPD and normal subjects

CB Cooper, GL Calligaro, MM Quinn… - Respiratory Physiology …, 2014 - Elsevier
In COPD, dynamic hyperinflation (DH) occurs during exercise and during metronome-paced
tachypnea (MPT). We investigated the relationship of DH with breathing pattern and …

Breathing pattern and gas exchange at peak exercise in COPD patients with and without tidal flow limitation at rest

O Diaz, C Villafranca, H Ghezzo… - European …, 2001 - Eur Respiratory Soc
Expiratory flow limitation (FL) at rest is frequently present in chronic obstructive pulmonary
disease (COPD) patients. It promotes dynamic hyperinflation with a consequent decrease in …

Partitioning of the elastic work of inspiration in patients with COPD during exercise

P Sliwinski, D Kaminski, J Zielinski… - European Respiratory …, 1998 - Eur Respiratory Soc
During exercise, dynamic hyperinflation-induced intrinsic positive end-expiratory pressure
(PEEPi) and decreased dynamic lung compliance (CL, dyn) of patients with chronic …

Airway obstruction, dynamic hyperinflation, and breathing pattern during incremental exercise in COPD patients

B Frisk, B Espehaug, JA Hardie, LI Strand… - Physiological …, 2014 - Wiley Online Library
Ventilatory capacity is reduced in chronic obstructive pulmonary disease (COPD) patients.
Tidal volume (VT) is lower and breathing frequency higher at a given ventilation (VE) …