Small-cell lung cancer (SCLC) is an aggressive lung tumor subtype with poor prognosis. We
sequenced 29 SCLC exomes, 2 genomes and 15 transcriptomes and found an extremely …

Small-cell lung cancer (SCLC) is an aggressive lung tumor subtype with poor prognosis,,.
We sequenced 29 SCLC exomes, 2 genomes and 15 transcriptomes and found an …

Genomic characterization efforts in small-cell lung cancer have been complicated by the
paucity of high-quality surgical resection specimens for this aggressive lung cancer subtype …

INTRODUCTION: Recent studies using next generation sequencing (NGS) technologies
have provided insights into the molecular landscape of small cell lung cancer (SCLC) …

Small cell lung cancer (SCLC) is a lethal form of lung cancer. Here, we develop a
quantitative multiplexed approach on the basis of lentiviral barcoding with somatic CRISPR …

Small Cell Lung Cancer accounts for nearly 15% of lung cancer incidence. Genomics
alterations of TP53 and RB1 genes are found in almost 80% of SCLC cases. The initial …

We performed whole-genome sequencing (WGS) of a case of early-stage small-cell lung
cancer (SCLC) to analyze the genomic features. WGS revealed a lot of single-nucleotide …

Small-cell lung cancer (SCLC) is an exceptionally aggressive disease with poor prognosis.
Here, we obtained exome, transcriptome and copy-number alteration data from …

7512 Background: Small cell lung cancer (SCLC) is an aggressive disease with poor
prognosis. There is an urgent need for detecting well-defined therapeutic targets, however …

The molecular profiling of small-cell lung cancer is challenging because of the difficulty in
obtaining suitable tumor samples for integrative genomic analysis. While an urgent need …