Alzheimer's disease (AD) is a progressive neurodegenerative disorder that destroys patient
memory and cognition, communication ability with the social environment and the ability to …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that destroys patient
memory and cognition, communication ability with the social environment and the ability to …

Oxidative stress and neuronal energy depletion are characteristic biochemical hallmarks of
Alzheimer's disease (AD). It is therefore conceivable that pro-energetic and antioxidant …

The aging process comprises a series of organic alterations, affecting multiple systems,
including the nervous system. Aging has been considered the main risk factor for the …

Objectives: α-lipoic acid (ALA) is a natural antioxidant which acts as a cofactor of
bioenergetic mitochondrial enzymes. Along with its mitochondrial action, ALA and its …

The naturally occurring antioxidant lipoic acid (LA) was first described as an essential
cofactor for the conversion of pyruvate to Acetyl-CoA, a critical step in respiration. LA is now …

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases with
motor disturbances, cognitive decline, and behavioral impairment. It is characterized by the …

Alzheimer's disease (AD) is a neurodegenerative disorder characterised by impairments in
the cognitive domains associated with orientation, recording, and memory. This pathology …

Diabetes mellitus (DM) is an important risk factor for Alzheimer′ s disease (AD). Most
diabetic patients have insulin resistance (IR) that is associated with compensatory …

Despite the existence of many preclinical studies, scientific evidence is lacking on the
clinical use of alpha-lipoic acid (ALA) for central nervous system disorders. Therefore, we …