In mammalian cells inhibition of the cdc2 function results in arrest in the G2-phase of the cell
cycle. Several cdc2-related gene products have been identified recently and it has been …

We have cloned two different human cDNAs that can complement cdc28 mutations of
budding yeast Saccharomyces cerevisiae. One corresponds to a gene encoding human …

The Xenopus cdk2 gene encodes a 32-kDa protein kinase with sequence similarity to the 34-
kDa product of the cdc2 gene. Previous studies have shown that the kinase activity of the …

We have analyzed the cell cycle regulation of human cyclin-dependent kinase 2 (CDK2), a
protein closely related to the cell cycle-regulatory protein kinase CDC2. We find that CDK2 …

We have examined the role of phosphorylation in the regulation of human cyclin‐dependent
kinase‐2 (CDK2), a protein closely related to the cell cycle regulatory kinase CDC2. We find …

In the cell cycle of fission and budding yeast, the p34cdc2/CDC28 kinase is required for both
the G1-to-S and G2-to-M phase transitions. In vertebrates, the homologous p34cdc2 kinase …

Critical cell cycle transitions are controlled by the coordinate actions of the p34cdc2 protein
kinase and its regulatory subunits, cyclins. Recently we identified another human p34 …

Using the yeast two-hybrid system we have identified novel potential Cdk4 interacting
proteins. Here we described the interaction of Cdk4 with a human homologue of the yeast …

The p34cdc2 protein kinase is known to regulate important transitions in the eukaryotic cell
cycle. We have identified 10 human protein kinases based on their structural relation to …

p33cdk2 is a serine-threonine protein kinase that associates with cyclins A, D, and E and
has been implicated in the control of the G1/S transition in mammalian cells. Recent …