Impaired glucose tolerance (IGT) serves as a marker for the state of insulin resistance and
predicts both large-and small-vessel vascular complications, independent of a patient's …

Despite abundant clinical evidence linking metabolic abnormalities to diabetic vasculopathy,
the molecular basis of individual susceptibility to diabetic vascular complications is still …

Despite improvements in glucose, lipids and blood pressure control, vascular complications
remain the most important cause of morbidity and mortality in patients with type 1 diabetes …

The endothelium produces multiple mediators that not only regulate blood pressure, but also
important physiological inflammatory processes such as the recruitment and activation of …

The endothelium is a complex organ with a multitude of properties essential for control of
vascular functions. Dysfunction of the vascular endothelium is regarded as an important …

Micro-and macrovascular complications are major causes of disability and death in patients
with diabetes mellitus. Functional impairment of endothelial activity precedes the …

Endothelial dysfunction plays a critical role in atherosclerosis progression, leading to
cardiovascular complications. There are significant associations between diabetes mellitus …

In patients with diabetes, atherosclerosis is the main reason for impaired life expectancy,
and diabetic nephropathy and retinopathy are the largest contributors to end-stage renal …

Abstract The International Diabetes Federation estimates that 316 million people are
currently affected by impaired glucose tolerance (IGT). Most importantly, recent forecasts …

Abstract Type 2 diabetes (T2D) markedly increases the risk of cardiovascular disease.
Endothelial dysfunction (ED), an early indicator of diabetic vascular disease, is common in …