3D QSAR and Docking Studies of Various Amido and Benzyl-substituted 3-amino-4-(2-cyanopyrrolidide) pyrrolidinyl Analogs as DPP-IV Inhibitors
R Agrawal, P Jain, S Narayan Dikshit… - Protein and Peptide …, 2013 - ingentaconnect.com
… class and our continuing interest in the development of DPP-IV inhibitors, a … 3D QSAR was
derived on the series of 3-amino-4-(2-cyanopyrrolidide) pyrrolidinyl analogs having DPP-IV …
derived on the series of 3-amino-4-(2-cyanopyrrolidide) pyrrolidinyl analogs having DPP-IV …
Design, Synthesis, Characterization and Pharmacological Evaluation of DPP-IV Inhibitors for Antidiabetic Activity.
R Srimathi - 2012 - repository-tnmgrmu.ac.in
… amidoand benzyl-substituted cis-3-amino-4-(2-cyanopyrrolidide)pyrrolidinyl DPP-IV
inhibitors… of exclusion volumes in Pharmacophore-baed 3D QSAR optimization. The result is to …
inhibitors… of exclusion volumes in Pharmacophore-baed 3D QSAR optimization. The result is to …
Recent medicinal chemistry approach for the development of dipeptidyl peptidase iv inhibitors
… We will focus mainly on DPP IV inhibitors in this review and scrutinize their … A series of
3-amino-4substituted pyrrolidines has been … Liu et al. synthesized a novel benzylsubstituted (S)-…
3-amino-4substituted pyrrolidines has been … Liu et al. synthesized a novel benzylsubstituted (S)-…
Dipeptidyl peptidase IV inhibitors: a new paradigm in type 2 diabetes treatment
S Janardhan, G Narahari Sastry - Current Drug Targets, 2014 - ingentaconnect.com
… 3D QSAR and Docking Studies of Various Amido and Benzyl-Substituted 3-amino-4-(2cyanopyrrolidide)Pyrrolidinyl
Analogs as DPP-IV Inhibitors. Protein Pept Lett 2013; 20(9): 1066-78…
Analogs as DPP-IV Inhibitors. Protein Pept Lett 2013; 20(9): 1066-78…
Structure based lead optimization approach in discovery of selective DPP4 inhibitors
M Ghate, SV Jain - Mini Reviews in Medicinal Chemistry, 2013 - ingentaconnect.com
… Recently, cis-3-amino-4-(2-cyanopyrrolidide)-pyrrolidines … chain of Asn710 and the amide
carbonyl interacted with the side-… the development of DPP IV inhibitors. Compounds previously …
carbonyl interacted with the side-… the development of DPP IV inhibitors. Compounds previously …
Integrated protocol to design potential inhibitors of dipeptidyl peptidase-4 (DPP-4)
SQ Pantaleão, EA Philot… - Current Topics in …, 2020 - ingentaconnect.com
… be used in the construction of 3D QSAR (CoMFA and CoMSIA, … The docking poses of all
analogues and their interactions … selective αamino amide dipeptidyl peptidase IV inhibitor for the …
analogues and their interactions … selective αamino amide dipeptidyl peptidase IV inhibitor for the …
Comparative atom-based 3D QSAR study of 3-nitro-1H-1,2,4-triazole-based aliphatic and aromatic amines analogs for its anti-trypanosomal activities
… The 3D QSAR is classified as indirect drug design. The 3D QSAR helps in identification of
… The detail datasets used for the preparation of all three selected 3D QSAR hypothesis and …
… The detail datasets used for the preparation of all three selected 3D QSAR hypothesis and …
Recent advances in the development of pharmaceutical agents for metabolic disorders: a computational perspective
S Janardhan, V Dubovskaja, A Lagunin… - Current Medicinal …, 2018 - ingentaconnect.com
… 3 inhibitors [267]. Zhu et al. identified potent imidazopyrazinone analogs based on docking
studies … [274] have demonstrated the 3D-QSAR analysis on a series of gliptins, pyrrolidines, β-…
studies … [274] have demonstrated the 3D-QSAR analysis on a series of gliptins, pyrrolidines, β-…