9-Cis-retinoic acid induces growth inhibition in retinoid-sensitive breast cancer and sea urchin embryonic cells via retinoid X receptor α and replication factor C3

S Maeng, GJ Kim, EJ Choi, HO Yang… - Molecular …, 2012 - academic.oup.com
inhibitory effect of 9-cis-RA on cell proliferation depends on 9-cis-RA-dependent interaction
of retinoid X receptor α (RXRα) with replication factor C3 … the circular proliferating cell nuclear …

Effects of 9-cis-retinoic acid on the proliferation and apoptosis of cutaneous T-cell lymphoma cells

H Yang, Y Tao, M Zhang, P Ma, L Li, Q Diao - Anti-cancer drugs, 2019 - journals.lww.com
… by retinoic acid receptors (RAR) and/or retinoid X receptors (… with 10% heat-inactivated
fetal bovine serum, 100 IU/ml … -cis-RA inhibited cell growth and induced apoptosis and cell

Antitumoral effects of 9-cis retinoic acid in adrenocortical cancer

…, EI Buzás, A Falus, I Kovalszky, A Patócs… - Cellular and molecular …, 2014 - Springer
… associated with reduced retinoic acid production and retinoid X receptor-mediated signaling…
might inhibit hormone secretion and cell proliferation in the NCI-H295R cell line, and induce

[HTML][HTML] Multifaceted regulation and functions of replication factor C family in human cancers

…, X Wang, Y Zhang, J Jiang, F Zhang, X Qi - … Journal of Cancer …, 2018 - ncbi.nlm.nih.gov
… Moreover, RFC1 overexpression can prevent cell death induced by … unload PCNA and
inhibit DNA polymerase activity, and its … retinoid X receptor α (RXRα) and participate in cis-retinoic …

Replication factor C3 is a CREB target gene that regulates cell cycle progression through the modulation of chromatin loading of PCNA

HD Chae, B Mitton, NJ Lacayo, KM Sakamoto - Leukemia, 2015 - nature.com
induced by 9-cis-retinoic acid-activated retinoid X receptor α (RXR α) resulted in growth
inhibition of retinoic acid-sensitive breast cancer and embryonic cells through suppression of S …

[HTML][HTML] Evaluation of 9-cis retinoic acid and mitotane as antitumoral agents in an adrenocortical xenograft model

…, KF Medzihradszky, K Rácz, A Patócs… - … Journal of Cancer …, 2015 - ncbi.nlm.nih.gov
… the NCI-H295R ACC cell line and found that 9-cis retinoic acid (9-… manner, and it induced
significant gene expression changes [7]. … Protein SET is an inhibitor of tumor suppressor PP2A (…

Characterization of a sea urchin IQ Motif Containing Protein D as a coactivator of nuclear receptors

MA Kim, YC Sohn - Zoological science, 2017 - BioOne
… the bait protein in the presence of 9-cis retinoic acid. Here, we describe IQ motif … -sensitive
breast cancer and sea urchin embryonic cells via retinoid X receptor α and replication factor C3

[HTML][HTML] Nuclear receptors and development of marine invertebrates

A Miglioli, L Canesi, IDL Gomes, M Schubert… - Genes, 2021 - mdpi.com
sea urchin Strongylocentrotus nudus, for example, an ambulacrarian deuterostome, knockdown
of RXR induces abnormal early embryonic development … also activate or inhibit ERs, …

[HTML][HTML] shRNA-mediated silencing of the RFC3 gene suppresses hepatocellular carcinoma cell proliferation

Z Yao, K Hu, HE Huang, S Xu… - International …, 2015 - spandidos-publications.com
… expression levels of replication factor C, subunit … induced by 9-cis retinoic acid-activated
retinoid X receptor α (RXRα) has been shown to inhibit the growth of cancer and embryonic cells

RFC3 serves as a novel prognostic biomarker and target for head and neck squamous cell carcinoma

KR Avs, C Pandi, B Kannan, A Pandi… - Clinical Oral …, 2023 - Springer
… The role of the replication factor C subunit 3 (RFC3) in HNSCC … the inhibitory effect of 9-cis
retinoic acid–activated retinoid X … This effect appears to stem from the induction of cell cycle …